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NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. 再加上，我们可以发NQO1 试剂盒 (30) 和 NQO1 蛋白 (16)和数多这个蛋白质的别的产品。
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Dog (Canine) Monoclonal NQO1 Primary Antibody for FACS, ICC - ABIN152344
Siegel, Franklin, Ross: Immunohistochemical detection of NAD(P)H:quinone oxidoreductase in human lung and lung tumors. in Clinical cancer research : an official journal of the American Association for Cancer Research 1998
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Human Polyclonal NQO1 Primary Antibody for ELISA, WB - ABIN184714
Asher, Lotem, Kama, Sachs, Shaul: NQO1 stabilizes p53 through a distinct pathway. in Proceedings of the National Academy of Sciences of the United States of America 2002
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Dog (Canine) Polyclonal NQO1 Primary Antibody for ELISA, WB - ABIN249473
Singh, Zahid, Saeed, Gaikwad, Meza, Cavalieri, Rogan, Chakravarti: NAD(P)H:quinone oxidoreductase 1 Arg139Trp and Pro187Ser polymorphisms imbalance estrogen metabolism towards DNA adduct formation in human mammary epithelial cells. in The Journal of steroid biochemistry and molecular biology 2009
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Human Polyclonal NQO1 Primary Antibody for IF (p), IHC (p) - ABIN678428
Wang, Peng, Wei, Wei, Wang, Ma, Yao, Fu, Zu: Geraniin exerts cytoprotective effect against cellular oxidative stress by upregulation of Nrf2-mediated antioxidant enzyme expression via PI3K/AKT and ERK1/2 pathway. in Biochimica et biophysica acta 2015
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Human Monoclonal NQO1 Primary Antibody for FACS, IHC - ABIN969319
Kansanen, Jyrkkänen, Volger, Leinonen, Kivelä, Häkkinen, Woodcock, Schopfer, Horrevoets, Ylä-Herttuala, Freeman, Levonen: Nrf2-dependent and -independent responses to nitro-fatty acids in human endothelial cells: identification of heat shock response as the major pathway activated by nitro-oleic acid. in The Journal of biological chemistry 2009
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Mouse (Murine) Monoclonal NQO1 Primary Antibody for ICC, FACS - ABIN1042634
Siegel, Ross: Immunodetection of NAD(P)H:quinone oxidoreductase 1 (NQO1) in human tissues. in Free radical biology & medicine 2001
Human Polyclonal NQO1 Primary Antibody for WB - ABIN1686087
La Sala, Pujadas, De Nigris, Canivell, Novials, Genovese, Ceriello: Oscillating glucose and constant high glucose induce endoglin expression in endothelial cells: the role of oxidative stress. in Acta diabetologica 2014
Human Polyclonal NQO1 Primary Antibody for ICC, IF - ABIN441361
Oh, Kim, Kim, Kim, Lee, Hong, Goodwin, Ruthenborg, Jung, Lee, Lee, Park, Kim, Park: NQO1 inhibits proteasome-mediated degradation of HIF-1α. in Nature communications 2016
Coptisine exerted its antioxidant activity against AAPH-induced toxicity involving in activating Akt (显示 AKT1 抗体) and JNK (显示 MAPK8 抗体)/Nrf2 (显示 NFE2L2 抗体)/NQO1 pathway.
Results show that H80R causes a population shift in the conformational ensemble of apo (显示 C9orf3 抗体)-P187S, remodelling the structure and dynamics of the FAD (显示 BRCA2 抗体)-binding site and reducing the energetic penalization arising from the equilibrium between apo (显示 C9orf3 抗体)- and holo-states.
The C609T polymorphism within NQO1 is independently associated with CAD (显示 CAD 抗体) in women, but no association was observed in whole study population or in men.
This study suggests that HNC (显示 MMP8 抗体) samples should be screened for NQO1 expression to identify patients that will likely benefit from combined therapy with beta-lap and IR.
The results indicate that NQO1*2 genotype may increase susceptibility to DN in north Indian subjects with T2DM.
Thus, our findings indicated that NQO1 could stabilize Herp (显示 HERPUD1 抗体) protein expression via indirect regulation of synoviolin.
NQO1 and GCLC (显示 GCLC 抗体) were both functionally sufficient to autonomously confer a tamoxifen-resistant metabolic phenotype, characterized by i) increased mitochondrial biogenesis, ii) increased ATP production and iii) reduced glutathione levels.
NQO1 induces hepatocellular carcinoma cell apoptosis and proliferation inhibition through the AMPK (显示 PRKAA1 抗体)/PGC-1alpha (显示 PPARGC1A 抗体) pathway.
the expression of NRF2 (显示 GABPA 抗体), KEAP1 (显示 KEAP1 抗体), NQO-1 and HO-1 (显示 HMOX1 抗体) are increased significantly in advanced laryngeal squamous cell carcinoma, compared with the adjacent normal mucosa. Remarkable relevance exists between high expression of KEAP1 (显示 KEAP1 抗体), NQO-1, HO-1 (显示 HMOX1 抗体) and nuclear NRF2 (显示 GABPA 抗体). their expression levels were independent of age, tumor stage (clinical stage III and IV), tumor size and lymph node metastasis.
(i) melatonin counteracted UVR-induced alterations in the ATP synthesis and reduced free radical formation; (ii) melatonin induced the translocation of Nrf2 (显示 GABPA 抗体) transcription factor from the cytosol into the nucleus resulting in, (iii) melatonin enhanced gene expression of phase-2 antioxidative enzymes including gamma-glutamylcysteine synthetase (显示 GCLC 抗体) (gamma-GCS (显示 GCLC 抗体)), heme oxygenase-1 (HO-1 (显示 HMOX1 抗体)), and NADPH: quinone dehydrogenase-1 (NQO1...
Coptisine exerted its antioxidant activity against AAPH-induced toxicity involving in activating Akt (显示 AKT1 抗体) and JNK (显示 MAPK8 抗体)/Nrf2 (显示 GABPA 抗体)/NQO1 pathway.
NQO1 and autophagy participate in a protective role in cisplatin injury.
A significant increase was found in Nrf2 (显示 NFE2L2 抗体)-ARE activity after partial hepatectomy (PHx). The signal maximum was recorded on the third day after PHx. Significantly more hepatocytes were positive for Nrf2 (显示 NFE2L2 抗体) and HO-1 (显示 HMOX1 抗体) on the third postoperative day compared with baseline levels. The mRNA expression of HO-1 (显示 HMOX1 抗体) and NQO1 were significantly increased on day 3.
Miroestrol restored hepatic NQO1 expression in beta-naphthoflavone-treated mice.
previous and present results collectively show that NQO1 is involved in the formation of tight junctions in the small intestine, and that defects in NQO1 enhance C. difficile toxin A-induced acute inflammatory responses, presumably via the loss of epithelial cell tight junctions
NQO1 plays a critical role in protection against energy depletion in acetaminophen-induced liver injury, and is associated with improvement of mitochondrial dysfunction
The present results demonstrate that exacerbated cisplatin-induced nephrotoxicity under the NQO1-knockout condition was accompanied by the reduced expression of MRN complex proteins, ATM (显示 ATM 抗体), PARP1 (显示 PARP1 抗体), and Sirt1 (显示 SIRT1 抗体).
Taken together, these data suggest that EEEC attenuates oxidative stress by activating Nrf2 (显示 NFE2L2 抗体)-mediated HO-1 (显示 HMOX1 抗体) and inducing NQO-1 via the activation of MAPK (显示 MAPK1 抗体) signaling pathways.
We defined the basal and butylated hydroxyanisole induced expression patterns of Nqo1, AKR1B8, and Ho-1 (显示 HMOX1 抗体) in the liver and small intestine of C57BL/6 mice.
The colons of NQO1-KO mice also showed high levels of reactive oxygen species (ROS (显示 ROS1 抗体)) and histone deacetylase (HDAC (显示 HDAC1 抗体)) activity, which are known to affect transcriptional regulation.
the induction of cellular NAD(+) levels using beta-lapachone (beta-Lap), whose intracellular target is NQO1, prevents the toxic effects of cisplatin through the regulation of PARP-1 (显示 PARP1 抗体) and SIRT1 (显示 SIRT1 抗体) activity.
The obtained data convincingly showed that porcine NADPH-d cells may produce nitric oxide.
Immunoreactivity of eNOS (显示 NOS3 抗体) was similar to NADPH-d staining. Clear iNOS (显示 NOS2 抗体) immunoreactivity was detected in the luminal epithelium, endometrial stroma and individual endometrial glands.
NQO1 expression was increased in the ruminal papillae of more efficient low residual feed intake (RFI (显示 RNF34 抗体)) animals compared to the high RFI (显示 RNF34 抗体) animals
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
NAD(P)H dehydrogenase [quinone] 1
, NAD(P)H menadione oxidoreductase 1, dioxin-inducible
, NAD(P)H dehydrogenase, quinone 1
, NAD(P)H:quinone oxidoreductase 1
, menadione reductase
, phylloquinone reductase
, quinone reductase 1
, nad(p)h dehydrogenase (quinone) 1
, NAD(P)H:Quinone acceptor oxidoreductase type 1
, NAD(P)H:menadione oxidoreductase 1
, NAD(P)H:quinone oxireductase
, diaphorase (NADH/NADPH) (cytochrome b-5 reductase)
, dioxin-inducible 1
, Diaphorase (NADH/NADPH)
, NAD(P)H:menadione oxidoreductase
, NAD(P)H dehydrogenase (quinone)
, NAD(P)H menadione oxidoreductase 1, dioxin inducible
, diaphorase 4 (NADH/NADPH)
, nicotinamide adenine dinucleotide phosphate diaphorase
, diaphorase 4
, NAD(P)H: quinone oxidoreductase 1