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NQO1 抗体 (C-Term)

NQO1 适用: 人, 小鼠, 大鼠 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854666
发货至: 中国
  • 抗原 See all NQO1 抗体
    NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
    抗原表位
    • 16
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 64
    • 32
    • 31
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 55
    • 7
    • 2
    • 2
    克隆类型
    • 49
    • 17
    多克隆
    标记
    • 40
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NQO1 antibody is un-conjugated
    应用范围
    • 53
    • 24
    • 14
    • 14
    • 12
    • 12
    • 9
    • 9
    • 8
    • 6
    • 4
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    猪, 猕猴, 牛, 豚鼠
    交叉反应 (详细)
    Pig (92 %), Rhesus Monkey (100 %), Bovine (83 %), Guinea pig (100 %)
    产品特性
    Rabbit Polyclonal antibody to NQO1 (NAD(P)H dehydrogenase, quinone 1)
    NQO1 antibody [C2C3], C-term
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human NQO1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product NQO1 Primary Antibody
  • 应用备注
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    说明

    Positive Control: Molt-4 , Raji , mouse heart , rat heart

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Ishitsuka, Huebner, Rice, Koch, Speransky, Steven, Roop: "Lce1 Family Members Are Nrf2-Target Genes that Are Induced to Compensate for the Loss of Loricrin." in: The Journal of investigative dermatology, Vol. 136, Issue 8, pp. 1656-1663, (2017) (PubMed).

  • 抗原
    NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
    别名
    NQO1 (NQO1 产品)
    别名
    zgc:77191 antibody, wu:fb63c10 antibody, nqo1 antibody, DHQU antibody, DIA4 antibody, DTD antibody, NMOR1 antibody, NMORI antibody, QR1 antibody, Dia4 antibody, AV001255 antibody, Dtd antibody, Nmo-1 antibody, Nmo1 antibody, Nmor1 antibody, Ox-1 antibody, Ox1 antibody, Qr1 antibody, NADPH-d antibody, NAD(P)H dehydrogenase, quinone 1 antibody, NAD(P)H quinone dehydrogenase 1 antibody, NAD(P)H dehydrogenase, quinone 1 L homeolog antibody, nqo1 antibody, NQO1 antibody, Bpet2092 antibody, nqo1.L antibody, Nqo1 antibody
    背景
    This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    Cellular Localization: Cytoplasm
    分子量
    31 kDa
    基因ID
    1728
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