anti-Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) 抗体

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. 再加上,我们可以发Mitochondrially Encoded NADH Dehydrogenase 4 蛋白 (3)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MT-ND4 4538 P03905
MT-ND4 17719 P03911
MT-ND4    
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产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
小鼠 非结合性 WB Western blot analysis of extracts of various cells, using MT-ND4 antibody. 100 μL Log in to see 16 Days
$323.13
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非结合性 WB   200 μL Log in to see 13至14个工作日
$487.50
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小鼠 非结合性 ELISA, WB Western Blot detection against Immunogen (32.05 KDa) . 50 μL Log in to see 11至12个工作日
$298.57
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非结合性 IHC, IHC (p), WB Western Blot: MT-ND4 Antibody [NBP2-47365] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10. Lane 2: Human cell line HepG2 Immunohistochemistry: MT-ND4 Antibody [NBP2-47365] - Analysis of human stomach, upper shows strong cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10至13个工作日
$439.69
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通过反应活性、应用领域、克隆类型和共轭标记 MT-ND4 抗体

特性 应用范围 宿主 克隆类型
Human
,

Mouse (Murine)


Rat (Rattus)


更多抗Mitochondrially Encoded NADH Dehydrogenase 4的相互作用对抗体

Human Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) interaction partners

  1. A missense mutation, m.11778G>A (p.R340H), in the ND4 gene was identified in eight patients and three asymptomatic carriers, even though the incidence of this has been considered low in Chinese population.

  2. MT-ND4 and MT-TL1 (显示 TNFSF15 抗体) genetic variation might be associated with male infertility in Chinese patients.

  3. this paper identified m.11240C4T in ND4 as a novel mitochondrial disease-related mtDNA mutation in Leigh syndrome.

  4. We identified a genetic association between the MT-ND4 11719 A/G polymorphism and Ulcerative Colitis in the subgroup of males. The male-specific association indicates differences between males and females concerning the impact of mitochondrial gene polymorphisms on the development of Ulcerative Colitis.

  5. The molecular study of a family with one member with Leber hereditary optic neuropathy found the mitochondrial mutation m.11778G>A in MT-ND4.

  6. the ND4 gene is the hot spot for mutations associated with Leber's hereditary optic neuropathy

  7. Three mutations were significantly related to the presence of epilepsy. These mutations were found at the 8502, 11994, and 13,231 bp of mtDNA, which resulted in amino acid changes at the MT-ATP-8, MT-ND4 and MT-ND5 (显示 MT-ND5 抗体) genes.

  8. Expression of WT human ND4 in cells with the G11778A mutation in ND4 led to restoration of defective ATP synthesis.

  9. altered activity of complex III modulates the phenotypic manifestation of Leber's hereditary optic neuropathy-associated ND4 G11778A mutation

  10. Patients with somatically acquired ND4 mutations had significantly longer relapse-free survival (P=0.017) and overall survival (OS) (P=0.021) than ND4(wildtype) patients

Mouse (Murine) Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) interaction partners

  1. Cybrid mice showed normal respiratory function whether or not their mtDNA possessed the A11181G mutation of the mt-Nd4 gene, suggesting that the this mutation is not responsible for respiration defects found in SAMP8 mice.

Arabidopsis thaliana Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) interaction partners

  1. Data indicate that SLOW GROWTH 4 (SLO4) is a mitochondrial pentatricopeptide repeat (PPR (显示 PTH1R 抗体)) protein that is involved in editing NADH dehydrogenase subunit 4 (nad4), possibly required for the efficient splicing of NADH dehydrogenase subunit 2 (nad2 (显示 MT-ND2 抗体)) intron1.

  2. The data supports a model for MTSF1 functioning in which its association with the last nucleotides of the nad4 3' untranslated region stabilizes nad4 mRNA.

Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) 抗原简介

蛋白简介

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).

Gene names and symbols associated with MT-ND4

  • NADH dehydrogenase, subunit 4 (complex I) (ND4) 抗体
  • NADH dehydrogenase subunit 4 (ND4) 抗体
  • NADH dehydrogenase subunit 4 (nad4) 抗体
  • NADH dehydrogenase subunit 4 (NAD4) 抗体
  • NADH dehydrogenasesubunit 4 (nad4) 抗体
  • MTND4 抗体
  • NADH4 抗体

Protein level used designations for MT-ND4

NADH dehydrogenase subunit 4

GENE ID SPECIES
4538 Homo sapiens
17719 Mus musculus
3283886 Bos taurus
804483 Canis lupus familiaris
807643 Gallus gallus
808510 Sus scrofa
808225 Oryctolagus cuniculus
2565705 Caenorhabditis elegans
814596 Arabidopsis thaliana
807666 Ascaris suum
807960 Locusta migratoria
802562 Candida albicans SC5314
808213 Branchiostoma lanceolatum
1734028 Acanthamoeba castellanii
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