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Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. 再加上，我们可以发Killer Cell Lectin-Like Receptor Subfamily C, Member 2 蛋白 (14) 和 Killer Cell Lectin-Like Receptor Subfamily C, Member 2 试剂盒 (1)和数多这个蛋白质的别的产品。
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Human Monoclonal KLRC2 Primary Antibody for FACS - ABIN4898785
Moraru, Black, Muntasell, Portero, López-Botet, Reyburn, Pandey, Vilches et al.: NK Cell and Ig Interplay in Defense against Herpes Simplex Virus Type 1: Epistatic Interaction of CD16A and IgG1 Allotypes of Variable Affinities Modulates Antibody-Dependent Cellular Cytotoxicity ... in Journal of immunology (Baltimore, Md. : 1950) 2015
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Human Monoclonal KLRC2 Primary Antibody for FACS - ABIN4898777
Nielsen, White, Bottomley, Lusa, Rodríguez-Galán, Turner, Goodier, Riley: Impaired NK Cell Responses to Pertussis and H1N1 Influenza Vaccine Antigens in Human Cytomegalovirus-Infected Individuals. in Journal of immunology (Baltimore, Md. : 1950) 2015
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Human Monoclonal KLRC2 Primary Antibody for FACS - ABIN4900831
Horowitz, Guethlein, Nemat-Gorgani, Norman, Cooley, Miller, Parham: Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation. in Journal of immunology (Baltimore, Md. : 1950) 2015
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Human Monoclonal KLRC2 Primary Antibody for FACS - ABIN4898781
Katano, Takahashi, Ito, Kamisako, Mizusawa, Ka, Ogura, Suemizu, Kawakami, Ito: Predominant development of mature and functional human NK cells in a novel human IL-2-producing transgenic NOG mouse. in Journal of immunology (Baltimore, Md. : 1950) 2015
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Human Monoclonal KLRC2 Primary Antibody for FACS - ABIN4898779
Zhou, Amran, Kramski, Angelovich, Elliott, Hearps, Price, Jaworowski: An NK Cell Population Lacking FcR? Is Expanded in Chronically Infected HIV Patients. in Journal of immunology (Baltimore, Md. : 1950) 2015
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Human Polyclonal KLRC2 Primary Antibody for EIA, WB - ABIN453719
Seo, Park, Nam, Bang, Sohn, Lee, Park: Association of CD94/NKG2A, CD94/NKG2C, and its ligand HLA-E polymorphisms with Behcet's disease. in Tissue antigens 2007
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the data of this study extend the characterization of adaptive NK cell subsets that differentiate in response to human Cytomegalovirus, supporting a relationship between their distribution and NKG2C copy number
The new method offers the potential to use SNP arrays from genome wide association studies to study the frequency of KLRC2 deletion in other populations and its association with other diseases
Assessment of NK cell repertoires in 60 NKG2C(-/-) donors revealed a broad range of NK cell populations displaying characteristic footprints of adaptive NK cells, including a terminally differentiated phenotype, functional reprogramming, and epigenetic remodeling of the interferon (IFN)-gamma (显示 IFNA 抗体) promoter.
HLA-E (显示 HLAE 抗体) regulates NKG2C+ natural killer cell function through presentation of a restricted peptide repertoire
Data suggest the proinflammatory potential of NKG2C(bright) NK cells.
lack of expression of NKG2C may be associated with altered control of human cytomegalovirus infection in childhood
No difference in the prevalence of NKG2C deletion was observed.
NKG2C receptor deletion and a functional polymorphism in its ligand HLA-E may play a role in psoriasis susceptibility
NKG2C(hi)CD57 (显示 B3GAT1 抗体)+ NK cells respond specifically to acute infection with cytomegalovirus and not Epstein-Barr virus.
NKG2C zygosity influences CD94 (显示 KLRD1 抗体)/NKG2C receptor function and the NK-cell compartment redistribution in response to human cytomegalovirus.
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined.
CD159 antigen-like family member C
, NK cell receptor C
, NKG2-C type II integral membrane protein
, NKG2-C-activating NK receptor