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anti-Coagulation Factor VIII (F8) 抗体

F8 encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation\; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. 再加上,我们可以发Factor VIII 试剂盒 (51)Factor VIII 蛋白 (33)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
F8 14069 Q06194
F8 2157 P00451
F8 302470  

antibodies-online.cn销售最多的anti-Factor VIII 抗体

Showing 10 out of 338 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
小鼠 非结合性 ELISA Detection limit for recombinant GST tagged F8 is approximately 3 ng/mL as a capture antibody. 0.1 mg Log in to see 15至20个工作日
¥3,179.71
详细
非结合性 ICC, IF, IHC, IHC (p), WB Western Blot: Factor VIII antibody (S2194) [ABIN4493381] - in extracts from HuvEc cells. Immunocytochemistry/Immunofluorescence: Factor VIII Antibody [ABIN4493381] - Factor VIII antibody was tested 1:50 in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). Image objective 40x. 0.1 mg Log in to see 25至31个工作日
¥3,869.96
详细
非结合性 IF (p), IHC (p) Formalin-fixed and paraffin embedded rat tibia tissue labeled with Anti-Factor VIII (FVIII) Polyclonal Antibody (ABIN668601) , Unconjugated at 1:300, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed : Mouse C57 cells labeled with Anti- Factor VIII (FVIII) Polyclonal Antibody (ABIN668601) , Unconjugated at 1:300, followed by conjugation to the secondary antibody was Goat Anti-Rabbit IgG, PE conjugated  at 1:200 for 40 minutes at 37 °C DAPI (5 µg/mL, blue) was used to stain the cell nuclei 100 μL Log in to see 9至12个工作日
¥2,709.56
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非结合性 IF (p), IHC (p) Formalin-fixed and paraffin embedded human skin labeled with Anti-Factor VIII Polyclonal Antibody, Unconjugated (ABIN872493) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 9至12个工作日
¥2,709.56
详细
非结合性 IHC, ELISA, WB 0.1 mg Log in to see 24至32个工作日
¥3,526.50
详细
小鼠 非结合性 EIA, RIA, WB   0.5 mg Log in to see 29至35个工作日
¥5,902.42
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非结合性 IF (cc), IF (p), IHC (p) Formalin-fixed and paraffin embedded:human colon carcinoma labeled with Anti-factor VIII(FVIII) (human) Polyclonal Antibody (ABIN728000), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded:human colon carcinoma labeled with Anti-factor VIII(FVIII)(human) Polyclonal Antibody , Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 9至12个工作日
¥2,709.56
详细
小鼠 非结合性 EIA, IHC (fro), WB   0.5 mg Log in to see 29至35个工作日
¥4,893.43
详细
小鼠 非结合性 ELISA, WB Figure 1: Western blot analysis using F8 mouse mAb against truncated Trx-F8 recombinant protein (1) . 100 μL Log in to see 24至29个工作日
¥9,896.74
详细
小鼠 非结合性 ELISA, WB   100 μL Log in to see 32至37个工作日
¥4,016.80
详细

通过反应活性、应用领域、克隆类型和共轭标记 F8 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-Factor VIII 抗体

  1. Human Monoclonal Factor VIII Primary Antibody for ELISA - ABIN394620 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN394620

  2. Dog (Canine) Polyclonal Factor VIII Primary Antibody for IF (p), IHC (p) - ABIN668601 : Yu, Zhang, Jiang, Wang, Zhang: Astragalosides promote angiogenesis via vascular endothelial growth factor and basic fibroblast growth factor in a rat model of myocardial infarction. in Molecular medicine reports 2015 (PubMed)
    Show all 3 references for ABIN668601

  3. Human Monoclonal Factor VIII Primary Antibody for EIA, RIA - ABIN120341 : Rotblat, OBrien, OBrien, Goodall, Tuddenham: Purification of human factor VIII:C and its characterization by Western blotting using monoclonal antibodies. in Biochemistry 1985 (PubMed)
    Show all 2 references for ABIN120341

  4. Human Polyclonal Factor VIII Primary Antibody for IF (cc), IF (p) - ABIN728000 : Zhou, Zhu, Zou, Wang: Changes in number and biological function of endothelial progenitor cells in hypertension disorder complicating pregnancy. in Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2008 (PubMed)
    Show all 2 references for ABIN728000

  5. Human Polyclonal Factor VIII Primary Antibody for IF (p), IHC (p) - ABIN872493 : Tang, Liu, Dong, Li, Li, Hou, Zheng, Lin, Ren: Protective Effect of Kaempferol on LPS plus ATP-Induced Inflammatory Response in Cardiac Fibroblasts. in Inflammation 2014 (PubMed)
    Show all 2 references for ABIN872493

  6. Human Polyclonal Factor VIII Primary Antibody for ICC, IF - ABIN449338 : Zhu, Liu, Miao, Qu, Chi: Enhanced plasma factor VIII activity in mice via cysteine mutation using dual vectors. in Science China. Life sciences 2012 (PubMed)
    Show all 2 references for ABIN449338

  7. Human Monoclonal Factor VIII Primary Antibody for ELISA, WB - ABIN969123 : Shovlin, Sulaiman, Govani, Jackson, Begbie: Elevated factor VIII in hereditary haemorrhagic telangiectasia (HHT): association with venous thromboembolism. in Thrombosis and haemostasis 2007 (PubMed)
    Show all 2 references for ABIN969123

  8. Dog (Canine) Polyclonal Factor VIII Primary Antibody for IHC, ELISA - ABIN1582291 : Shen, Li, Chung, Gillies: Retinal vascular changes after glial disruption in rats. in Journal of neuroscience research 2010 (PubMed)

  9. Human Monoclonal Factor VIII Primary Antibody for EIA, IHC (fro) - ABIN112268 : Stel, van der Kwast, Veerman: Detection of factor VIII/coagulant antigen in human liver tissue. in Nature 1983 (PubMed)

更多抗Factor VIII的相互作用对抗体

Zebrafish Coagulation Factor VIII (F8) interaction partners

  1. gene is flanked by factor VII (显示 TH 抗体) and factor X genes; gene encodes a protein homologous to factor VII (显示 TH 抗体), but lacks critical residues for factor VII (显示 TH 抗体) activity; functions as an inhibitor of blood coagulation in biochemical assays using zebrafish or human plasmas

Mouse (Murine) Coagulation Factor VIII (F8) interaction partners

  1. data demonstrate that infusion of platelets containing FVIII triggers neither primary nor memory anti-FVIII immune response in FVIII(null) mice

  2. Both platelet-VWF (显示 VWF 抗体) and plasma-VWF (显示 VWF 抗体) are required for optimal platelet-derived FVIII gene therapy for hemophilia A in the presence of inhibitors.

  3. These data support the investigation of FVIII orthologs as treatment modalities in both the congenital and acquired FVIII inhibitor settings.

  4. Activatable bioengineered FIX molecules with FVIII-independent activity might be a promising tool for improving hemophilia A treatment, especially for patients with inhibitors.

  5. This study demonstrated that FVIIIa interacts with Low-density lipoprotein receptor-related protein 1 (显示 LRP1 抗体) cluster III.

  6. a fragment containing only approximately 20% of the VWF (显示 VWF 抗体) sequence is sufficient to support FVIII stability in vivo

  7. Endothelial cells from multiple, but not all, tissues contribute to the plasma FVIII pool in the mouse.

  8. Endothelial cells are the predominant, and possibly exclusive, source of plasma FVIII.

  9. Micro-computed tomography analysis of distal tibia metaphyses also revealed for the first time a major impact of the FVIII/thrombin (显示 F2 抗体)/PAR1 (显示 F2R 抗体) axis on the dynamic bone structure, showing reduced bone.

  10. Findings indicate that improving protein trans-splicing by inter-chain disulfide bonding is a promising approach for increasing the efficacy of dual-vector based FVIII gene transfer.

Human Coagulation Factor VIII (F8) interaction partners

  1. The FVIII B domain variants, p.D963N, p.S806T, p.G873D, p.H998Q and p.Q1225R may be considered as polymorphism or non-pathologic mutations in patients with Haemophilia A.

  2. In this meta-analysis, we have assessed the association between the FXIII-A Val34Leu polymorphism and intracerebral hemorrhage risk. The results of a combined analysis showed no significant association between the FXIII-A Val34Leu polymorphism and ICH (显示 COL4a2 抗体) risk in the overall population. The results of this meta-analysis suggest that the FXIII-A Val34Leu polymorphism is not associated with ICH (显示 COL4a2 抗体) risk in a Caucasian population.

  3. von Willebrand factor (显示 VWF 抗体) binds to the surface of dendritic cells and modulates peptide presentation of factor VIII.

  4. Desmopressin acetate increases F8 plasma concentration in patients with combined deficiency of factors V and VIII (显示 COX8A 抗体).

  5. 37 (70%) of the 53 had discordant antigen-activity ratio, majority of those mutations produced FVIII with low FVIII-specific activity. However, 4 (7.5%) of the 53 mutations produced higher specific activity of FVIII. It is possible that these mutations either produce a secretory defect or an increased metabolic turnover to account for the low levels of FVIII with these mutations.

  6. Platelet-targeted FVIII gene therapy has higher therapeutic efficacy compared to factor VIII replacement therapy may be due to accelerated thrombin (显示 F2 抗体) generation.

  7. Letter: report deep intronic variants of factor VII (显示 TH 抗体) gene in hemophilia A.

  8. Coagulation test results showed that the presence of double Glu113Asp, Arg593Cys mutations has a slightly synergistic effect on FVIII activity.

  9. Report a dose-response relationship between high FVIII levels and risk of death in venous thrombosis patients and in individuals from the general population.

  10. Case Report: P1809L mutation in A3 induced the conformational change in the FVIII molecule that hampered antigenic determinant(s) located in the C2 domain and might result in the inhibitor development.

Pig (Porcine) Coagulation Factor VIII (F8) interaction partners

  1. thrombin (显示 F2 抗体) stimulates transglutaminase activity in articular cartilage by directly cleaving factor XIII (显示 UGDH 抗体) and by receptor-mediated up-regulation of factor XIII (显示 UGDH 抗体) synthesis

  2. cupredoxin-like A1 subdomains in fVIII contain inter-species differences that are a result of selective pressure on the dissociation rate constant

Cow (Bovine) Coagulation Factor VIII (F8) interaction partners

  1. Factor VIIIc (显示 COX7A2 抗体) is responsible for tissue invasion during tumor progression.

Factor VIII (F8) 抗原简介

蛋白简介

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation\; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

Gene names and symbols associated with F8

  • coagulation factor VIIi (f7i) 抗体
  • coagulation factor VIII (F8) 抗体
  • coagulation factor VIII, procoagulant component (F8) 抗体
  • AHF 抗体
  • Cf-8 抗体
  • Cf8 抗体
  • DXS1253E 抗体
  • F8B 抗体
  • F8C 抗体
  • fb61d02 抗体
  • FVIII 抗体
  • HEMA 抗体
  • wu:fb61d02 抗体

Protein level used designations for F8

Factor VIII , procoagulant component , antihemophilic factor , coagulation factor VIII , coagulation factor VIIIc , factor VIII F8B , coagulation factor VIII, procoagulant component (hemophilia A) , factor VIII , coagulation co-factor

GENE ID SPECIES
282671 Danio rerio
14069 Mus musculus
2157 Homo sapiens
397339 Sus scrofa
403875 Canis lupus familiaris
100271720 Bos taurus
100303761 Oryctolagus cuniculus
302470 Rattus norvegicus
100359363 Ovis aries
422199 Gallus gallus
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