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CBX4 抗体

(Chromobox Homolog 4 (CBX4))
E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones\; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
CBX4 抗体  (AA 397-514) CBX4 抗体  (AA 397-514) CBX4 抗体 (AA 397-514) (ABIN5542423)

CBX4 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 6C5G3 unconjugated

CBX4 抗体  (AA 1-160) CBX4 抗体  (AA 1-160) CBX4 抗体 (AA 1-160) (ABIN7150950)

CBX4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

CBX4 抗体  (AA 401-500) CBX4 抗体  (AA 401-500) CBX4 抗体 (AA 401-500) (ABIN2559520)

CBX4 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

CBX4 抗体 by 适用

Find CBX4 抗体 for a variety of species such as anti-Human CBX4, anti-Mouse CBX4, anti-Dog CBX4. The species listed below are among those available. Click on a link to go to the corresponding products.

CBX4 抗体 by 应用范围

Find CBX4 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

CBX4 抗体 by 抗体来源

Find CBX4 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

CBX4 抗体 by 抗原表位

Find CBX4 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

CBX4 抗体 by 克隆形成能力

Find available monoclonal or polyclonal CBX4 抗体. Click on a link to go to the corresponding products.

CBX4 抗体 by 克隆

Find CBX4 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

CBX4 抗体 by 标记

Find CBX4 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular CBX4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS
Validations
  • (6)
Cat. No. ABIN5542423
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7150950
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro)
Validations
  • (1)
  • (1)
Cat. No. ABIN2559520
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7150954
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN948698
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN6138017
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (2)
  • (2)
Cat. No. ABIN389086
Quantity 400 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB, IHC
Validations
  • (1)
  • (2)
Cat. No. ABIN2779230
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Human, Mouse, Pig, Rabbit
Application IHC, IF, IHC (p)
Validations
  • (1)
Cat. No. ABIN2618071
Quantity 50 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Human, Monkey, Mouse, Pig, Rabbit
Application WB, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN6755404
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
  • (1)
Cat. No. ABIN389087
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, IC
Validations
  • (2)
Cat. No. ABIN7306480
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN2559521
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN6976674
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN6977535
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our CBX4 抗体

Han, Wang, Li, Dong, Zhang, Yan: "HIF-1α SUMOylation affects the stability and transcriptional activity of HIF-1α in human lens epithelial cells." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 253, Issue 8, pp. 1279-90, (2015) (PubMed).

Peuget, Bonacci, Soubeyran, Iovanna, Dusetti: "Oxidative stress-induced p53 activity is enhanced by a redox-sensitive TP53INP1 SUMOylation." in: Cell death and differentiation, Vol. 21, Issue 7, pp. 1107-18, (2014) (PubMed).

Hao, Midic, Garriga, Latham: "Contribution of CBX4 to cumulus oophorus cell phenotype in mice and attendant effects in cumulus cell cloned embryos." in: Physiological genomics, Vol. 46, Issue 2, pp. 66-80, (2014) (PubMed).

Ismail, Gagné, Caron, McDonald, Xu, Masson, Poirier, Hendzel: "CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage." in: Nucleic acids research, Vol. 40, Issue 12, pp. 5497-510, (2012) (PubMed).

Oh, Kim, Mouradian, Chung: "Human Polycomb protein 2 promotes ?-synuclein aggregate formation through covalent SUMOylation." in: Brain research, Vol. 1381, pp. 78-89, (2011) (PubMed).

Yang, Sharrocks: "The SUMO E3 ligase activity of Pc2 is coordinated through a SUMO interaction motif." in: Molecular and cellular biology, Vol. 30, Issue 9, pp. 2193-205, (2010) (PubMed).

Vincenz, Kerppola: "Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 43, pp. 16572-7, (2008) (PubMed).

Jones, Fusi, Higham, Abdel-Hafiz, Horwitz, Lam, Brosens: "Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 44, pp. 16272-7, (2006) (PubMed).

Kagey, Melhuish, Wotton: "The polycomb protein Pc2 is a SUMO E3." in: Cell, Vol. 113, Issue 1, pp. 127-37, (2003) (PubMed).

Aliases for CBX4 抗体

chromobox 4 (CBX4) 抗体
chromobox 4 (Cbx4) 抗体
chromobox 4 S homeolog (cbx4.S) 抗体
chromobox homolog 4 (CBX4) 抗体
chromobox homolog 4 (Pc class homolog, Drosophila) (cbx4) 抗体
cbx4-a 抗体
im:6911625 抗体
MPc2 抗体
NBP16 抗体
PC2 抗体
XPolycomb 抗体
zgc:158588 抗体
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