anti-C-Type Lectin Domain Family 4, Member D (CLEC4D) 抗体

CLEC4D encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. 再加上,我们可以发CLEC4D 蛋白 (10)CLEC4D 试剂盒 (1)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CLEC4D 338339 Q8WXI8
CLEC4D 17474 Q9Z2H6
CLEC4D 362432 Q69FH1

antibodies-online.cn销售最多的anti-CLEC4D 抗体

Showing 10 out of 66 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
小鼠 Allophycocyanin FACS Detection of CLEC4D/CLECSF8 in Whole Blood Monocytes by Flow Cytometry. Whole blood monocytes were stained with Mouse Anti-Human CLEC4D/CLECSF8 APC-conjugated Monoclonal Antibody. Detection of CLEC4D/CLECSF8 in Whole Blood Monocytes by Flow Cytometry. Whole blood monocytes were stained with Mouse Anti-Human CLEC4D/CLECSF8 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 26至31个工作日
¥3,001.64
详细
小鼠 非结合性 FACS, WB Detection of CLEC4D/CLECSF8 in Human Monocytes by Flow Cytometry. Human whole blood monocytes were stained with Mouse Anti-Human CLEC4D/CLECSF8 Monoclonal Antibody. Detection of CLEC4D/CLECSF8 in Human Monocytes by Flow Cytometry. Human whole blood monocytes were stained with Mouse Anti-Human CLEC4D/CLECSF8 Monoclonal Antibody. 100 μg Log in to see 26至31个工作日
¥2,144.03
详细
非结合性 WB 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
小鼠 PE FACS Detection of CLEC4D/CLECSF8 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human CLEC4D/CLECSF8 PE-conjugated Monoclonal Antibody. Detection of CLEC4D/CLECSF8 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human CLEC4D/CLECSF8 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 26至31个工作日
¥2,615.71
详细
非结合性 WB CLEC4D Antibody (Center)  western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the CLEC4D antibody detected the CLEC4D protein (arrow). 400 μL Log in to see 5至8个工作日
¥2,325.14
详细
非结合性 ELISA   100 μg Log in to see 14至15个工作日
¥2,680.04
详细
非结合性 IHC, WB 100 μL Log in to see 34至38个工作日
¥2,882.69
详细
山羊 非结合性 FACS, WB Detection of CLEC4D/CLECSF8 in Human Monocytes by Flow Cytometry. Human whole blood monocytes were stained with Goat Anti-Human CLEC4D/CLECSF8 Antigen Affinity-purified Polyclonal Antibody. Detection of CLEC4D/CLECSF8 in Human Monocytes by Flow Cytometry. Human whole blood monocytes were stained with Goat Anti-Human CLEC4D/CLECSF8 Antigen Affinity-purified Polyclonal Antibody. 100 μg Log in to see 26至31个工作日
¥3,044.52
详细
小鼠 Alexa Fluor 488 FACS   0.1 mg Log in to see 28至35个工作日
¥3,655.56
详细
小鼠 Alexa Fluor 350 FACS   0.1 mg Log in to see 28至35个工作日
¥3,655.56
详细

通过反应活性、应用领域、克隆类型和共轭标记 CLEC4D 抗体

特性 应用范围 宿主 克隆类型 标记
Human , , ,
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Mouse (Murine)


Rat (Rattus)


引用最多的anti-CLEC4D 抗体

  1. Human Monoclonal CLEC4D Primary Antibody for ELISA - ABIN1998795 : Arce, Martínez-Muñoz, Roda-Navarro, Fernández-Ruiz: The human C-type lectin CLECSF8 is a novel monocyte/macrophage endocytic receptor. in European journal of immunology 2004 (PubMed)

  2. Human Monoclonal CLEC4D Primary Antibody for FACS, WB - ABIN4900404 : Graham, Gupta, Schafer, Reid, Kimberg, Dennehy, Hornsell, Guler, Campanero-Rhodes, Palma, Feizi, Kim, Sobieszczuk, Willment, Brown: The C-type lectin receptor CLECSF8 (CLEC4D) is expressed by myeloid cells and triggers cellular activation through Syk kinase. in The Journal of biological chemistry 2012 (PubMed)

更多抗CLEC4D的相互作用对抗体

Human C-Type Lectin Domain Family 4, Member D (CLEC4D) interaction partners

  1. Results show the molecular mechanism of glycolipid recognition through C-type lectin (显示 MBL2 抗体) receptors, which may provide clues to rational design for effective adjuvants.

  2. CLECSF8 functions as an activation receptor on myeloid cells and associates with a novel adaptor molecule

  3. Cross-linking of the receptor leads to a rapid internalization suggesting that CLECSF8 constitutes and endocytic receptor.

Mouse (Murine) C-Type Lectin Domain Family 4, Member D (CLEC4D) interaction partners

  1. activation of CLRs Dectin-2 (显示 CLEC6A 抗体) and Dectin-3 by fungi infections triggers them for ubiquitination and degradation in a Syk (显示 SYK 抗体)-dependent manner.

  2. The authors report that microbial stimulation triggers Mincle (Clec4e (显示 CLEC4E 抗体)) expression through the myeloid differentiation primary response gene 88 (MyD88 (显示 MYD88 抗体)) pathway; a process that does not require MCL (Clecsf8, Clec4d). Conversely, they show that MCL is constitutively expressed but retained intracellularly until Mincle (显示 CLEC4E 抗体) is induced, whereupon the receptors form heterodimers which are translocated to the cell surface.

  3. Data show that Mincle (显示 CLEC4E 抗体), the inducible receptor for mycobacterial cord factor, is the key switch for the transition of macrophages from cytokine expression to high nitric oxide production.

  4. MCL regulates the development of vaccine-induced Th17 cells and protective immunity against lethal experimental infection with Blastomyces dermatitidis.

  5. major contributor to activation of innate immunity against M. bovis in experimental model, mirrors Mincle (显示 CLEC4E 抗体) expression

  6. Clecsf8-/- mice exhibit higher bacterial burdens and increased mortality upon Mycobacterium tuberculosis infection.

  7. These results suggest that MCL positively regulates Mincle (显示 CLEC4E 抗体) expression through protein-protein interaction via its stalk region, thereby magnifying Mincle (显示 CLEC4E 抗体)-mediated signaling.

  8. Trehalose 6,6'-dimycolate-induced Mincle (显示 CLEC4E 抗体) expression is dependent on Dectin-3-mediated NF-kappaB (显示 NFKB1 抗体) activation through the CARD9 (显示 CARD9 抗体)-BCL10 (显示 BCL10 抗体)-MALT1 (显示 MALT1 抗体) complex.

  9. Compared to their respective homodimers, Dectin-3 and Dectin-2 (显示 CLEC6A 抗体) heterodimers bound alpha-mannans more effectively, leading to potent inflammatory responses against fungal infections.

  10. Clec4d(-/-) neutrophils did not exhibit any defect in bacterial clearance

CLEC4D 抗原简介

蛋白简介

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Gene names and symbols associated with CLEC4D

  • C-type lectin domain family 4, member D (CLEC4D) 抗体
  • C-type lectin domain family 4, member d (Clec4d) 抗体
  • C-type lectin domain family 4, member D (Clec4d) 抗体
  • CLEC-6 抗体
  • CLEC4D 抗体
  • CLEC6 抗体
  • Clecsf8 抗体
  • Mcl 抗体
  • Mpcl 抗体

Protein level used designations for CLEC4D

C-type lectin domain family 4, member D , C-type lectin domain family 4 member D , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 8 , C-type lectin receptor , C-type lectin superfamily member 8 , C-type lectin-like receptor 6 , macrophage C-type lectin , C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 8 , C-type lectin, superfamily member 8 , macrophage-restricted C-type lectin

GENE ID SPECIES
473405 Pan troglodytes
611536 Canis lupus familiaris
616646 Bos taurus
338339 Homo sapiens
17474 Mus musculus
362432 Rattus norvegicus
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