anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) 抗体

CTCF is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. 再加上,我们可以发CTCF 试剂盒 (9)CTCF 蛋白 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CTCF 13018 Q61164
CTCF 10664 P49711
CTCF 83726 Q9R1D1
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antibodies-online.cn销售最多的anti-CTCF 抗体

Showing 10 out of 96 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 ChIP, WB Chromatin Immunoprecipitation (ChIP) Using CTCF Antibody - N-terminal region (ARP38820_P050) and HCT116 Cells 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 ChIP, WB <b>WB Suggested Anti-CTCF Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Transfected 293T Chromatin Immunoprecipitation (ChIP) Using CTCF Antibody - N-terminal region (P100757_P050) and HCT116 Cells 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB Host: Rabbit Target Name: CTCF Sample Tissue: Mouse Spleen Antibody Dilution: 1ug/ml Host: Rabbit Target Name: CTCF Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 IHC (p), WB Anti-CTCF Picoband antibody, IHC(P) IHC(P): Human Lung Cancer Tissue Anti-CTCF Picoband antibody, IHC(P) IHC(P): Mouse Intestine Tissue 100 μg Log in to see 4至6个工作日
$240.00
详细
小鼠 非结合性 IF, WB Western blot analysis of CTCF on a Jurkat cell lysate (Human T-cell leukemia, ATCC TIB-152). Lane 1, 1:500, lane 2: 1: 1000, lane 3: 1: 2000 dilution of the mouse anti-CTCF antibody. Immunofluorescence staining of A431 cells (Human epithelial carcinoma, ATCC CRL-1555). 50 μg Log in to see 6至8个工作日
$154.07
详细
非结合性 IP 100 μL Log in to see 7至9个工作日
$486.94
详细
Bat 非结合性 IHC (p), WB Human Lung (formalin-fixed, paraffin-embedded) stained with CTCF antibody ABIN214093 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Skin (formalin-fixed, paraffin-embedded) stained with CTCF antibody ABIN214093 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7至9个工作日
$676.50
详细
小鼠 非结合性 ELISA, WB Figure 1: Western blot analysis using CTCF mouse mAb against A31 (1), MCF-7 (2), Hela (3), HCT116 (4), Jurkat (5), NIH/3T3 (6), and Cos7 (7) cell lysate. 100 μL Log in to see 2至3个工作日
$393.80
详细
Bat 非结合性 WB 50 μg Log in to see 7至9个工作日
$551.83
详细
非结合性 ELISA, WB Anti-CTCF in Western Blot using Immunochemical affinity purified Anti-CTCF antibody shows detection of CTCF in H929 nuclear cell lysates. Primary antibody was diluted to 1.2 µg/mL. 3% BSA from p/n BSA-30 (Bovine Serum Albumin Solution) was used for blocking. Secondary antibody anti-Rabbit IgG was used at 1:5,000. 25 μL Log in to see 1至2个工作日
$135.00
详细

通过反应活性、应用领域、克隆类型和共轭标记 CTCF 抗体

特性 应用范围 宿主 克隆类型
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Rat (Rattus) , ,
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引用最多的anti-CTCF 抗体

  1. Human Monoclonal CTCF Primary Antibody for IF, WB - ABIN968757 : Bell, West, Felsenfeld: The protein CTCF is required for the enhancer blocking activity of vertebrate insulators. in Cell 1999 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal CTCF Primary Antibody for IF, WB - ABIN968758 : Filippova, Fagerlie, Klenova, Myers, Dehner, Goodwin, Neiman, Collins, Lobanenkov: An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes. in Molecular and cellular biology 1996 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal CTCF Primary Antibody for ELISA, WB - ABIN969071 : Grbesa, Marinkovic, Ivkic, Kruslin, Novak-Kujundzic, Pegan, Bogdanovic, Bedekovic, Gall-Troselj: Loss of imprinting of IGF2 and H19, loss of heterozygosity of IGF2R and CTCF, and Helicobacter pylori infection in laryngeal squamous cell carcinoma. in Journal of molecular medicine (Berlin, Germany) 2008 (PubMed)
    Show all 3 Pubmed References

  4. Human Monoclonal CTCF Primary Antibody for ELISA, WB - ABIN965942 : Majumder, Gomez, Chadwick, Boss: The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions. in The Journal of experimental medicine 2008 (PubMed)
    Show all 3 Pubmed References

  5. Human Polyclonal CTCF Primary Antibody for IP - ABIN153008 : Lai, Fatemi, Dhasarathy, Malone, Sobol, Geigerman, Jaye, Mav, Shah, Li, Wade: DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas. in The Journal of experimental medicine 2010 (PubMed)

  6. Human Polyclonal CTCF Primary Antibody for ChIPSeq, ChIP - ABIN2668282 : Moriguchi, Yu, Takai, Hayashi, Satoh, Suzuki, Ohneda, Yamamoto: The Human GATA1 Gene Retains a 5' Insulator That Maintains Chromosomal Architecture and GATA1 Expression Levels in Splenic Erythroblasts. in Molecular and cellular biology 2015 (PubMed)

  7. Human Polyclonal CTCF Primary Antibody for ChIP, ICC - ABIN4300770 : Martínez, Cruz, Lu, Plasschaert, Deng, Rivera-Molina, Bartolomei, Lieberman, Tang: CTCF binding to the first intron of the major immediate early (MIE) gene of human cytomegalovirus (HCMV) negatively regulates MIE gene expression and HCMV replication. in Journal of virology 2014 (PubMed)

更多抗CTCF的相互作用对抗体

Zebrafish CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) interaction partners

  1. We propose that cohesin and CTCF have distinct functions in the regulation of runx1 (显示 RUNX1 抗体) during zebrafish embryogenesis.

  2. Data conclude that CTCF modulates MRF (显示 C11orf9 抗体) functional interactions in the orchestration of myogenesis.

Mouse (Murine) CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) interaction partners

  1. CTCF mediates local regulatory interactions to coordinate transcriptional programs controlling transitions in morphology and function during heart development.

  2. Long-range promoter-enhancer interaction mediated by CTCF plays important roles in controlling the cell-to-cell variation of gene expression in mammalian cells.

  3. n keratinocytes, the promoter-enhancer anchoring regions in the gene-rich transcriptionally active TADs are enriched for the binding of chromatin architectural proteins CTCF, Rad21 (显示 RAD21 抗体) and chromatin remodeler Brg1 (显示 SMARCA4 抗体). In contrast to gene-rich TADs, gene-poor TADs show preferential spatial contacts with each other, do not contain active enhancers and show decreased binding of CTCF, Rad21 (显示 RAD21 抗体) and Brg1 (显示 SMARCA4 抗体) in keratinocytes

  4. CTCF mediated chromatin structural modulation and regulates Hoxc gene expression.

  5. CTCF can regulate V(D)J recombination by segregating recombination signal sequences (RSSs) into distinct loop domains and inhibiting RSS (显示 GRB10 抗体) synapsis, independent of any effects on transcription, RSS (显示 GRB10 抗体) accessibility, and RAG recombinase (显示 RAG1 抗体) tracking

  6. this study shows that CTCF serves to translate alpha-ketoglutarate-sensitive metabolic changes into context-dependent differentiation gene programs

  7. CTCF-cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo.

  8. ERCC1 (显示 ERCC1 抗体)-XPF (显示 ERCC4 抗体) cooperates with CTCF and cohesin to facilitate the developmental silencing of imprinted genes and that persistent DNA damage triggers chromatin changes that affect gene expression programs associated with NER (显示 NR1H2 抗体) disorders.

  9. BRD2 (显示 BRD2 抗体) acts to augment the boundary function of CTCF both by limiting the spread or range of enhancer activity and by physically preventing the formation of cross-boundary contacts genome-wide.

  10. Functional assessment of CTCF sites at cytokine-sensing mammary enhancers using CRISPR/Cas9 gene editing in mice has been reported.

Human CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) interaction partners

  1. CTCF-mediated long-range interactions are integral for a multitude of topological features of interphase chromatin, such as the formation of topologically associated domains, domain insulation, enhancer blocking and even enhancer function.

  2. Authors have identified two novel pro-tumorigenic roles (promoting cell survival and altering cell polarity) for genetic alterations of CTCF in endometrial cancer.

  3. Describe several protein-DNA complex structures of a human CTCF tandem zinc-finger array, explaining the adaptability of CTCF to sequence variations and the positiondependent effect of differential DNA methylation (显示 HELLS 抗体) at two cytosine residues, and revealing a potential function of C-terminal ZF8 and ZF9 (显示 KLF6 抗体) spanning across the DNA phosphate backbone.

  4. CCCTC-binding factor (CTCF) targets the binding sites within MYCN (显示 MYCN 抗体) promoter to facilitate its expression in neuroblastoma (显示 ARHGEF16 抗体) (NB) cells.

  5. we review recent high-resolution chromosome conformation capture and functional studies that have informed models of the spatial and regulatory compartmentalization of mammalian genomes, and discuss mechanistic models for how CTCF and cohesin control the functional architecture of mammalian chromosomes.

  6. GAD1 (显示 GAD1 抗体) is reactivated by DNA methylation (显示 HELLS 抗体), which provided a model for DNA methylation (显示 HELLS 抗体) and the active orchestration of oncogenic gene expression by CTCF in cancer cells.

  7. epigenetic factor CTCF-mediated chromatin remodeling regulates interactions between eye-specific PAX6 (显示 PAX6 抗体) and those genes that are induced/associated with cell differentiation to modulate corneal epithelial cell-specific differentiation

  8. Rta (显示 RBM9 抗体)-mediated decreased binding of CTCF in the viral genome is concurrent with virus reactivation. Via interfering with CTCF binding, in the host genome Rta (显示 RBM9 抗体) can function as a transcriptional repressor for gene silencing.

  9. although we were unable to detect HD-associated DNA methylation (显示 HELLS 抗体) alterations at queried sites, we found that DNA methylation (显示 HELLS 抗体) may be correlated to the age of disease onset in cortex tissues. Moreover, our data suggest that DNA methylation (显示 HELLS 抗体) may, in part, contribute to tissue-specific HTT (显示 HTT 抗体) transcription through differential CTCF occupancy.

  10. Data support the hypothesis that CTCF and cohesin SA-1 (显示 STAG1 抗体) have multiple roles in the regulation of gene expression during erythropoiesis.

CTCF 抗原简介

蛋白简介

This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CTCF

  • CCCTC-binding factor (CTCF) 抗体
  • CCCTC-binding factor (zinc finger protein) (ctcf) 抗体
  • CCCTC-binding factor (ctcf) 抗体
  • CCCTC-binding factor (Ctcf) 抗体
  • AW108038 抗体
  • CTCF 抗体
  • im:7152666 抗体
  • xctcf 抗体

Protein level used designations for CTCF

transcriptional repressor CTCF , CCCTC-binding factor (zinc finger protein) , transcriptional repressor CTCF-like , 11-zinc finger protein , CTCFL paralog , 11 zinc finger transcriptional repressor

GENE ID SPECIES
100053363 Equus caballus
415104 Danio rerio
454169 Pan troglodytes
100101689 Xenopus (Silurana) tropicalis
100224119 Taeniopygia guttata
100350641 Oryctolagus cuniculus
100465401 Ailuropoda melanoleuca
13018 Mus musculus
10664 Homo sapiens
396274 Gallus gallus
479684 Canis lupus familiaris
517097 Bos taurus
83726 Rattus norvegicus
100623274 Sus scrofa
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