anti-Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) 抗体

BUB1 encodes a kinase involved in spindle checkpoint function. 再加上,我们可以发BUB1 蛋白 (6)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
BUB1 699 O43683
BUB1 296137  
BUB1 12235 O08901

antibodies-online.cn销售最多的anti-BUB1 抗体

Showing 10 out of 139 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 EIA, IHC (p), WB 0.4 mL Log in to see 29至35个工作日
¥4,086.26
详细
非结合性 FACS, WB BUB1A Antibody (N-term) (ABIN651630) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the BUB1A antibody detected the BUB1A protein (arrow). BUB1A Antibody (N-term) (ABIN651630) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 5至8个工作日
¥2,325.14
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小鼠 小鼠 非结合性 ICC, FACS, IF, IHC (p), WB 50 μL Log in to see 25至30个工作日
¥4,212.41
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非结合性 IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma BUB1A Antibody (F1058) (ABIN392626) western blot analysis in T47D cell line lysates (35 µg/lane).This demonstrates the BUB1A antibody detected the BUB1A protein (arrow). 400 μL Log in to see 5至8个工作日
¥2,325.14
详细
非结合性 IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using BUB1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 24至29个工作日
¥3,026.87
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小鼠 非结合性 IF, IP, WB   50 μg Log in to see 29至35个工作日
¥4,187.20
详细
非结合性 WB Observed bind size: 122KD Anti-Bub1 Picoband antibody,  All lanes: Anti BUB1  at 0.5ug/ml WB: Recombinant Human BUB1 Protein 0.5ng Predicted bind size: 39KD Observed bind size: 39KD 100 μg Log in to see 26至32个工作日
¥2,919.96
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非结合性 IHC (p), WB 50 μg Log in to see 29至35个工作日
¥5,095.23
详细
非结合性 IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-Bub1 Polyclonal Antibody, Unconjugated (ABIN706541) at 1:200 followed by conjugation to the secondary antibody and DAB staining Lane 1: mouse liver lysates Lane 2: mouse brain lysates probed with Anti Bub1 Polyclonal Antibody, Unconjugated (ABIN706541) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 119kD. Observed band size: 119kD. 100 μL Log in to see 5至7个工作日
¥2,610.23
详细
非结合性 ELISA, WB   100 μg Log in to see 24至29个工作日
¥3,026.87
详细

通过反应活性、应用领域、克隆类型和共轭标记 BUB1 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-BUB1 抗体

  1. Human Polyclonal BUB1 Primary Antibody for EIA, IHC (p) - ABIN360514 : Shichiri, Yoshinaga, Hisatomi, Sugihara, Hirata: Genetic and epigenetic inactivation of mitotic checkpoint genes hBUB1 and hBUBR1 and their relationship to survival. in Cancer research 2002 (PubMed)
    Show all 5 references for 360514

  2. Mouse (Murine) Monoclonal BUB1 Primary Antibody for ICC, FACS - ABIN108553 : Liu, Hittle, Jablonski, Campbell, Yoda, Yen: Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis. in Nature cell biology 2003 (PubMed)
    Show all 4 references for 108553

  3. Human Monoclonal BUB1 Primary Antibody for IF, IP - ABIN181741 : Vanoosthuyse, Hardwick: Bub1 and the multilayered inhibition of Cdc20-APC/C in mitosis. in Trends in cell biology 2005 (PubMed)
    Show all 3 references for 181741

  4. Human Polyclonal BUB1 Primary Antibody for FACS, WB - ABIN651630 : Gambe, Matsunaga, Takata, Ono-Maniwa, Baba, Uchiyama, Fukui: A nucleolar protein RRS1 contributes to chromosome congression. in FEBS letters 2009 (PubMed)
    Show all 2 references for 651630

  5. Human Polyclonal BUB1 Primary Antibody for IHC (p), WB - ABIN392626 : Cayrol, Cougoule, Wright: The beta2-adaptin clathrin adaptor interacts with the mitotic checkpoint kinase BubR1. in Biochemical and biophysical research communications 2002 (PubMed)
    Show all 2 references for 392626

  6. Human Polyclonal BUB1 Primary Antibody for ELISA, WB - ABIN1452063 : Cahill, da Costa, Carson-Walter, Kinzler, Vogelstein, Lengauer: Characterization of MAD2B and other mitotic spindle checkpoint genes. in Genomics 1999 (PubMed)

  7. Human Polyclonal BUB1 Primary Antibody for IHC, ELISA - ABIN1533511 : Cahill, Lengauer, Yu, Riggins, Willson, Markowitz, Kinzler, Vogelstein: Mutations of mitotic checkpoint genes in human cancers. in Nature 1998 (PubMed)

更多抗BUB1的相互作用对抗体

Human Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) interaction partners

  1. Chromosomal rearrangement resulting in BUB1 haploinsufficiency identified in a patient with polycystic liver disease. BUB1 may imply germline causes of genetic instability in PLD (显示 PLD 抗体).

  2. Results report that BubR1 (显示 BUB1B 抗体) and RepoMan bind directly to PP2A (显示 PPP2R4 抗体)-B56 using an LSPIxE short linear motif (SLiM), where phosphorylation of the Ser (显示 SIGLEC1 抗体) residue enhances binding. RepoMan and BubR1 (显示 BUB1B 抗体) bind B56 using both hydrophobic and electrostatic interactions.

  3. Inhibition of Bub1 kinase impaired chromosome arm resolution but exerted only minor effects on mitotic progression or spindle assembly checkpoint function.

  4. Study shows that BUB1beta (显示 BUB1B 抗体) and PDZ binding kinase (显示 PBK 抗体) are up-regulated in breast cancer tumors and their expression is associated with improved overall survival (OS) in basal-like tumors but worse OS in luminal and untreated patients.

  5. Bub1 may be associated with cancer stem cell potential.

  6. Both Bub1 and BubR1 (显示 BUB1B 抗体) bind stably to Bub3 (显示 BUB3 抗体) that is required for kinetochore localization of the proteins

  7. Bub1-Plk1 (显示 PLK1 抗体)-mediated phosphorylation of Cdc20 (显示 CDC20 抗体) constitutes an anaphase-promoting complex or cyclosome-inhibitory mechanism that is parallel, but not redundant, to mitotic checkpoint (显示 BUB3 抗体) complex formation.

  8. Data show that mitotic checkpoint (显示 BUB3 抗体) kinase (显示 ATR 抗体) Bub1 is an active kinase regulated by intra-molecular phosphorylation at the P+1 loop.

  9. human BUB1 does not associate stably with the MAD2 (显示 MAD2L1 抗体) activator MAD1 (显示 MXD1 抗体) (also known as MAD1L1 (显示 MAD1L1 抗体)) and, although required for accelerating the loading of MAD1 (显示 MXD1 抗体) onto kinetochores, BUB1 is dispensable for the maintenance of steady-state levels of MAD1 (显示 MXD1 抗体) there

  10. MAD2L1 (显示 MAD2L1 抗体) and BUB1 may play important roles in breast cancer progression, and measuring the expression of these genes may assist the prediction of breast cancer prognosis.

Mouse (Murine) Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) interaction partners

  1. Bub1 coordinates checkpoint signalling by distinct domains for RZZ and BubR1 (显示 BUB1B 抗体) recruitment and localizes antagonistic checkpoint activities.

  2. It was shown that that Bub1 kinase activity integrates attachment error correction and mitotic checkpoint signaling by controlling the localization and activity of Aurora B kinase through phosphorylation of histone H2A at threonine 121.

  3. Results establish that Bub1 has oncogenic properties and suggest that Aurora B (显示 AURKC 抗体) is a critical target through which overexpressed Bub1 drives aneuploidization and tumorigenesis.

  4. It seems that Sgo1 (显示 SGOL1 抗体) sets up the centromeric protection mechanism in G2, but that its Bub1-dependent localisation to centromeres during mitosis is not required to maintain cohesion.

  5. mutations of Bub1 and BubR1 (显示 BUB1B 抗体) found in Brca2 (显示 BRCA2 抗体)- mutant mice indeed are responsible for the chromosome instability in Brca2 (显示 BRCA2 抗体)-mutated tumors

  6. Our data suggest that Bub1 is a critical spindle checkpoint protein that regulates accurate chromosome alignment and homolog disjunction in mammalian oocyte meiosis.

  7. Bub1 is important for mediating cell death when chromosomes missegregate.

  8. Bub1 is essential for proper chromosome segregation, a defect that can lead to severe phenotypes, including perinatal lethality and a predisposition to cancer.

  9. Data show that the anaphase-promoting complex is activated in an exponential fashion after germinal vesicle breakdown in oocytes and that this process is advanced by 5 hr in oocytes lacking Bub1.

  10. Bub1 dysfunction is linked to inherited aneuploidy in female germ cells and may contribute to the maternal age-related increase in aneuploidy and pregnancy loss.

BUB1 抗原简介

蛋白简介

This gene encodes a kinase involved in spindle checkpoint function. The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy and several forms of cancer.

Gene names and symbols associated with BUB1

  • budding uninhibited by benzimidazoles 1 homolog (yeast) (BUB1) 抗体
  • BUB1 mitotic checkpoint serine/threonine kinase (bub1) 抗体
  • BUB1 mitotic checkpoint serine/threonine kinase (BUB1) 抗体
  • BUB1 mitotic checkpoint serine/threonine kinase (Bub1) 抗体
  • budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Bub1) 抗体
  • AL022991 抗体
  • Bub1a 抗体
  • BUB1L 抗体
  • C80208 抗体
  • D2Xrf87 抗体
  • hBUB1 抗体
  • xbub1 抗体

Protein level used designations for BUB1

BUB1 budding uninhibited by benzimidazoles 1 homolog , mitotic checkpoint serine/threonine-protein kinase BUB1 , budding uninhibited by benzimidazoles 1 , budding uninhibited by benzimidazoles 1 homolog , mitotic spindle checkpoint kinase , putative serine/threonine-protein kinase , mBUB1

GENE ID SPECIES
100064049 Equus caballus
459484 Pan troglodytes
780291 Xenopus (Silurana) tropicalis
699 Homo sapiens
296137 Rattus norvegicus
12235 Mus musculus
100682599 Canis lupus familiaris
514777 Bos taurus
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