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BUB1 抗体 (AA 731-1085)

BUB1 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043764
发货至: 中国
  • 抗原 See all BUB1 抗体
    BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))
    抗原表位
    • 15
    • 10
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 731-1085
    适用
    • 70
    • 27
    • 6
    • 1
    人, 大鼠
    宿主
    • 60
    • 11
    克隆类型
    • 60
    • 11
    多克隆
    标记
    • 43
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BUB1 antibody is un-conjugated
    应用范围
    • 61
    • 38
    • 23
    • 13
    • 13
    • 13
    • 10
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Mitotic checkpoint serine/threonine-protein kinase BUB1(BUB1) detection. Tested with WB in Human,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Mitotic checkpoint serine/threonine-protein kinase BUB1(BUB1) detection. Tested with WB in Human,Rat.
    Gene Name: BUB1 mitotic checkpoint serine/threonine kinase
    Protein Name: Mitotic checkpoint serine/threonine-protein kinase BUB1
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human Bub1 recombinant protein (Position: V731-K1085). Human Bub1 shares 81% amino acid (aa) sequence identity with mouse Bub1.
    亚型
    IgG
    Top Product
    Discover our top product BUB1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for Bub1 is approximately 0.25 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))
    别名
    BUB1 (BUB1 产品)
    别名
    bub1a antibody, bub1l antibody, hbub1 antibody, xbub1 antibody, BUB1A antibody, BUB1L antibody, hBUB1 antibody, AL022991 antibody, Bub1a antibody, C80208 antibody, D2Xrf87 antibody, BUB1 mitotic checkpoint serine/threonine kinase antibody, BUB1, mitotic checkpoint serine/threonine kinase antibody, BUB1 antibody, bub1 antibody, Bub1 antibody
    背景
    BUB1, also known as mitotic checkpoint serine/threonine kinase, is an enzyme that in humans is encoded by the BUB1 gene. It is mapped to 2q13. BUB1 is first identified in genetic screens of Saccharomyces cerevisiae. The protein is bound to kinetochores and plays a key role in the establishment of the mitotic spindle checkpoint and chromosome congression. The mitotic checkpoint kinase is evolutionary conserved in organisms as diverse as Saccharomyces cerevisiae and humans. Loss-of-function mutations or absence of BUB1 has been reported to result in aneuploidy, chromosomal instability (CIN) and premature senescence. The protein kinase BUB1 possesses versatile and distinct functions during the cell cycle, mainly in the SAC and chromosome alignment during metaphase.

    Synonyms: Bub1 antibody|BUB1 budding uninhibited by benzimidazoles 1 homolog antibody|BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast) antibody|BUB1 mitotic checkpoint serine/threonine kinase antibody|BUB1, S. cerevisiae, homolog of antibody|BUB1_HUMAN antibody|BUB1A antibody|BUB1L antibody|Budding uninhibited by benzimidazoles 1 (yeast homolog) antibody|Budding uninhibited by benzimidazoles 1 homolog antibody|Budding uninhibited by benzimidazoles 1, S. cerevisiae, homolog of antibody|hBUB1 antibody|Homolog of mitotic checkpoint gene BUB1 antibody|Mitotic checkpoint gene BUB1 antibody|Mitotic checkpoint serine/threonine protein kinase BUB1 antibody|Mitotic checkpoint serine/threonine-protein kinase BUB1 antibody|Mitotic spindle checkpoint kinase antibody|Putative serine/threonine protein kinase antibody
    基因ID
    699
    UniProt
    O43683
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