anti-BCL2-Associated Athanogene (BAG1) 抗体

The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. 再加上,我们可以发BAG1 蛋白 (14)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
BAG1 573 Q99933
BAG1 297994 B0K019
BAG1 12017 Q60739
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Showing 10 out of 129 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-BAG1 Antibody Titration: 1.0 ug/ml Positive Control: 721_B Whole Cell BAG1 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 EIA, WB 0.4 mL Log in to see 6至8个工作日
$390.50
详细
非结合性 FACS, IF, IHC (p), WB Western blot analysis of BAG1 Antibody (C-term) (ABIN389451) in MDA-MB231 cell line lysates (35 µg/lane). BAG1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with BAG1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10至11个工作日
$324.50
详细
小鼠 非结合性 IF, WB Immunofluorescence of monoclonal antibody to BAG1 on HeLa cell (antibody concentration 35 µg/mL). Western Blot analysis of BAG1 expression in transfected 293T cell line by BAG1 monoclonal antibody (M02), clone 2D3. Lane 1: BAG1 transfected lysate(38.878 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8至11个工作日
$450.00
详细
非结合性 WB 0.1 mg Log in to see 6至8个工作日
$456.50
详细
非结合性 WB 0.1 mg Log in to see 6至8个工作日
$896.50
详细
小鼠 非结合性 IHC (p), WB   100 μg Log in to see 4至6个工作日
$240.00
详细
小鼠 非结合性 IF, WB Western blot analysis of BAG-1 on a HeLa cell lysate (Human cervical epitheloid carcinoma, ATCC CCL-2.2). Lane 1: 1:15,000, lane 2: 1:30,000, lane 3: 1:60,000 dilution of the mouse anti-human BAG-1 antibody. 50 μg Log in to see 6至8个工作日
$154.07
详细
非结合性 ICC, IHC (p), WB Anti-Bag1 antibody, IHC(P) IHC(P): Rat Intestine Tissue 100 μg Log in to see 4至6个工作日
$200.00
详细
非结合性 WB WB Suggested Anti-BAG1 Antibody Titration: 1.0 ug/ml Positive Control: Hela Whole Cell BAG1 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells 100 μL Log in to see 2至3个工作日
$289.00
详细

通过反应活性、应用领域、克隆类型和共轭标记 BAG1 抗体

特性 应用范围 宿主 克隆类型
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Mouse (Murine)
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引用最多的anti-BAG1 抗体

  1. Human Monoclonal BAG1 Primary Antibody for IF, WB - ABIN968687 : Takayama, Krajewski, Krajewska, Kitada, Zapata, Kochel, Knee, Scudiero, Tudor, Miller, Miyashita, Yamada, Reed: Expression and location of Hsp70/Hsc-binding anti-apoptotic protein BAG-1 and its variants in normal tissues and tumor cell lines. in Cancer research 1998 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal BAG1 Primary Antibody for WB - ABIN2477576 : Broström, Kronberg, Németh, Oxelbäck: The effect of shoulder muscle training in patients with recurrent shoulder dislocations. in Scandinavian journal of rehabilitation medicine 1992 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal BAG1 Primary Antibody for WB - ABIN2477577 : Liman, Ganesan, Dohm, Krajewski, Reed, Bähr, Wouters, Kermer: Interaction of BAG1 and Hsp70 mediates neuroprotectivity and increases chaperone activity. in Molecular and cellular biology 2005 (PubMed)
    Show all 4 Pubmed References

  4. Human Polyclonal BAG1 Primary Antibody for IHC, IHC (p) - ABIN4282935 : Aust, Pils, Polterauer, Horvat, Cacsire Castillo-Tong, Pils, Dudek, Schmid, Speiser, Reinthaller, Grimm: Expression of Bcl-2 and the antiapoptotic BAG family proteins in ovarian cancer. in Applied immunohistochemistry & molecular morphology : AIMM 2013 (PubMed)

更多抗BAG1的相互作用对抗体

Human BCL2-Associated Athanogene (BAG1) interaction partners

  1. Increased BAG-1 by PD-L1 (显示 CD274 抗体) confers resistance to tyrosine kinase (显示 TXK 抗体) inhibitor in non-small cell lung cancer via persistent activation of ERK (显示 EPHB2 抗体) signaling.

  2. BAG-4/SODD (显示 BAG4 抗体), HSP70 (显示 HSP70 抗体), and HSP90 (显示 HSP90 抗体) are potential prognostic markers in node-negative breast carcinoma that merit further research.

  3. interaction with Bag1 then shifts hERG (显示 KCNH2 抗体) degradation to the membrane-anchored E3 ligase TRC8 (显示 RNF139 抗体) and its E2-conjugating enzyme Ube2g2 (显示 UBE2G2 抗体), as determined by siRNA screening

  4. These results suggest that Bag1 and Bag3 (显示 BAG3 抗体) control the stability of the Hsc70 (显示 HSPA8 抗体)-client complex using at least two distinct protein-protein contacts, providing a previously under-appreciated layer of molecular regulation in the human Hsc70 (显示 HSPA8 抗体) system.

  5. Taken together, these data indicate that Bag-1 up-regulation is required to maintain apoptosis resistance in human cytomegalovirus-infected cells.

  6. the combined effects of BAG-1 and XPD (显示 ERCC2 抗体) polymorphisms on chemotherapy sensitivity and survival in patients with advanced non-small-cell lung cancer, which might be the important predictive markers for platinum-based chemotherapy efficacy.

  7. Bag-1 indirectly affects cell survival through c-Myc (显示 MYC 抗体) activated signalling that causes elevation of ornithine decarboxylase (显示 ODC1 抗体) levels, leading to an increase of the polyamine content.

  8. Overexpression of miR (显示 MLXIP 抗体)-138 inhibited cell proliferation by directly suppressing the expression of Bag-1.

  9. The expression of BAG-1 was upregulated in chronic non-eosinophilic rhinosinusitis.

  10. BAG-1 expression was high in esophageal carcinoma tissues compared to normal esophagus. After Eca109 cells were transfected with BAG-1-siRNA, the proliferation and invasive capabilities of the cells were decreased while the apoptosis rate was enhanced.

Mouse (Murine) BCL2-Associated Athanogene (BAG1) interaction partners

  1. The BAG-1 stabilizes F508del-CFTR by direct binding, probably competing out ubiquitin to partially avoid its proteasomal degradation.

  2. The membrane form of heparin binding EGF-like growth factor (显示 HBEGF 抗体) (ProHB-EGF (显示 EGF 抗体)) is most likely able to trigger the nuclear translocation of BAG-1 in keeping its level high.

  3. Hemoxygenase (显示 HMOX1 抗体) 1 deficiency provoked diminished Bag-1 level upon LPS (显示 TLR4 抗体) treatment

  4. this study first reported the solution structure of mBAG-1 (显示 LRRC4 抗体)-UBH and the growth factor precursor-interacting motif on the protein.

  5. Bag-1 proteins function as regulators of the action of selective transcription factors.

  6. during development of mouse autopods, BAG-1 expression is downregulated upon the initiation of interdigital apoptosis (BAG-1)

  7. Bag1 is a regulator and marker of neuronal differentiation

  8. BAG1 displays potent neuroprotective activity in vivo against stroke.

  9. Since, BAG-1 is essential for cell survival, its association with tNhtt aggregates might disrupt its normal function and thereby promote polyglutamine-expanded tNhtt-induced cell death.

  10. Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells.

BAG1 抗原简介

蛋白简介

The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.

Gene names and symbols associated with BAG1

  • putative bcl2-associated athanogene (Smp_005900) 抗体
  • bcl2-associated athanogene, putative (Smp_031560) 抗体
  • BCL2 associated athanogene 1 (BAG1) 抗体
  • BCL-2-associated athanogene 1 (BAG1) 抗体
  • Bcl2 associated athanogene 1 (Bag1) 抗体
  • BAG family molecular chaperone regulator 1 (LOC781741) 抗体
  • BCL2-associated athanogene 1 (Bag1) 抗体
  • BAG family molecular chaperone regulator 1 (bag-1) 抗体
  • ATBAG1 抗体
  • Bag-1 抗体
  • BCL-2-associated athanogene 1 抗体
  • HAP 抗体
  • MSG15.15 抗体
  • MSG15_15 抗体
  • Rap46 抗体

Protein level used designations for BAG1

bcl2-associated athanogene , BCL2-associated athanogene , BAG family molecular chaperone regulator 1 , Bcl-2 associating athanogene-1 protein , Bcl-2-binding protein , glucocortoid receptor-associated protein RAP46 , receptor-associated protein, 46-KD , bcl-2-associated athanogene 1

GENE ID SPECIES
8342092 Schistosoma mansoni
8350429 Schistosoma mansoni
100345469 Oryctolagus cuniculus
835281 Arabidopsis thaliana
573 Homo sapiens
297994 Rattus norvegicus
781741 Bos taurus
611781 Canis lupus familiaris
12017 Mus musculus
172373 Caenorhabditis elegans
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