ZYX 抗体
(Zyxin (ZYX))
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| ZYX 抗体 (AA 1-572) | 人 | 小鼠 Monoclonal |
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| ZYX 抗体 (AA 1-572) | 人 | 小鼠 Monoclonal |
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| ZYX 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ZYX 抗体 (AA 1-300) | 人 | 兔 Polyclonal |
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| ZYX 抗体 (AA 1-573) | 人, 小鼠 | 小鼠 Monoclonal |
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| Recombinant ZYX 抗体 | 人 | 兔 Monoclonal |
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| ZYX 抗体 (AA 1-572) | 人 | 兔 Polyclonal |
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| ZYX 抗体 (Middle Region) | 人, 大鼠, Cow, 犬, 豚鼠, 马, 兔 | 兔 Polyclonal |
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| ZYX 抗体 | 人 | 兔 Monoclonal |
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| ZYX 抗体 (Internal Region) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ZYX 抗体 (AA 1-572) | 人 | 小鼠 Polyclonal |
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| ZYX 抗体 (AA 1-572) | 人, 小鼠, 大鼠, Hamster | 小鼠 Monoclonal |
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| ZYX 抗体 (Middle Region) | 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 | 兔 Polyclonal |
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| ZYX 抗体 (pSer142, pSer143) | 人 | 兔 Polyclonal |
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| ZYX 抗体 (AA 251-300) | 人, Cow, 豚鼠, 兔 | 兔 Polyclonal |
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| ZYX 抗体 (AA 307-356) | 人, 小鼠, 大鼠, Cow, 马, Bat, 猴 | 兔 Polyclonal |
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| ZYX 抗体 (AA 1-572) | 人 | 小鼠 Polyclonal |
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| ZYX 抗体 | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
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| ZYX 抗体 (Internal Region) | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
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| ZYX 抗体 (Internal Region) | 人 | 山羊 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- RNAi (RNA Interference: 所列应用)
2 references - 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 2C10-4A7
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 1-572
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- ISt (Immunostaining: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 2D1
- 标记
- unconjugated
- 抗体亚型
- IgG2a
- 抗原表位
- AA 1-572
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-300
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (fp) (Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections): 有验证图片)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 2D1
- 标记
- unconjugated
- 抗体亚型
- IgG2a kappa
- 抗原表位
- AA 1-573
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- 质量等级
- KD Validated
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 25GB3585
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-572
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- 适用
- 人, 大鼠, Cow, 犬, 豚鼠, 马, 兔
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Middle Region
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Internal Region
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-572
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ICC (Immunocytochemistry: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠, 大鼠, Hamster
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 164D4
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 1-572
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Middle Region
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pSer142, pSer143
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-572
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- AFfirm8057
- 标记
- unconjugated
- 抗体亚型
- IgG1
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- AFfirm8373
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- Internal Region
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 质量等级
- Verified
- 适用
- 人
- 宿主
- 山羊
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Internal Region
Latest Publications for our ZYX 抗体
: "Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin." in: Scientific reports, Vol. 6, pp. 23258, (2016) (PubMed).
: "NBR1 enables autophagy-dependent focal adhesion turnover." in: The Journal of cell biology, Vol. 212, Issue 5, pp. 577-90, (2016) (PubMed).
: "α-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation." in: PLoS ONE, Vol. 10, Issue 4, pp. e0120616, (2015) (PubMed).
: "Cell shape-dependent early responses of fibroblasts to cyclic strain." in: Biochimica et biophysica acta, Vol. 1833, Issue 12, pp. 3415-25, (2013) (PubMed).
: "Zyxin is a transforming growth factor-? (TGF-?)/Smad3 target gene that regulates lung cancer cell motility via integrin ?5?1." in: The Journal of biological chemistry, Vol. 287, Issue 37, pp. 31393-405, (2012) (PubMed).
: "Cell-penetrating peptides with intracellular actin-remodeling activity in malignant fibroblasts." in: The Journal of biological chemistry, Vol. 285, Issue 10, pp. 7712-21, (2010) (PubMed).
: "Domain analysis of alpha-actinin reveals new aspects of its association with F-actin during cytokinesis." in: Experimental cell research, Vol. 316, Issue 12, pp. 1925-34, (2010) (PubMed).
: "Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis." in: Molecular biology of the cell, Vol. 20, Issue 13, pp. 3115-24, (2009) (PubMed).
: "mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes." in: American journal of physiology. Renal physiology, Vol. 296, Issue 2, pp. F418-26, (2009) (PubMed).
: "Targeted disruption of the mouse Lipoma Preferred Partner gene." in: Biochemical and biophysical research communications, Vol. 379, Issue 2, pp. 368-73, (2009) (PubMed).
: "NBR1 enables autophagy-dependent focal adhesion turnover." in: The Journal of cell biology, Vol. 212, Issue 5, pp. 577-90, (2016) (PubMed).
: "α-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation." in: PLoS ONE, Vol. 10, Issue 4, pp. e0120616, (2015) (PubMed).
: "Cell shape-dependent early responses of fibroblasts to cyclic strain." in: Biochimica et biophysica acta, Vol. 1833, Issue 12, pp. 3415-25, (2013) (PubMed).
: "Zyxin is a transforming growth factor-? (TGF-?)/Smad3 target gene that regulates lung cancer cell motility via integrin ?5?1." in: The Journal of biological chemistry, Vol. 287, Issue 37, pp. 31393-405, (2012) (PubMed).
: "Cell-penetrating peptides with intracellular actin-remodeling activity in malignant fibroblasts." in: The Journal of biological chemistry, Vol. 285, Issue 10, pp. 7712-21, (2010) (PubMed).
: "Domain analysis of alpha-actinin reveals new aspects of its association with F-actin during cytokinesis." in: Experimental cell research, Vol. 316, Issue 12, pp. 1925-34, (2010) (PubMed).
: "Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis." in: Molecular biology of the cell, Vol. 20, Issue 13, pp. 3115-24, (2009) (PubMed).
: "mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes." in: American journal of physiology. Renal physiology, Vol. 296, Issue 2, pp. F418-26, (2009) (PubMed).
: "Targeted disruption of the mouse Lipoma Preferred Partner gene." in: Biochemical and biophysical research communications, Vol. 379, Issue 2, pp. 368-73, (2009) (PubMed).
Aliases for ZYX 抗体
Zyxin (zyx-1) 抗体Zyxin (Zyx) 抗体
zyxin (zyx) 抗体
zyxin (ZYX) 抗体
zyxin (EDI_201420) 抗体
zyxin (Zyx) 抗体
zyxin S homeolog (zyx.S) 抗体
9530098H06Rik 抗体
BcDNA:LD06023 抗体
CG32018 抗体
DLim-1 抗体
Dmel\\CG32018 抗体
DmLIM-1 抗体
ESP-2 抗体
HED-2 抗体
lim 抗体
Lim102EF 抗体
MGC145270 抗体
R75157 抗体
zgc:171680 抗体
ZYX 抗体
zyx 抗体
ZYX102 抗体
Zyx102 抗体
zyx102 抗体
Zyx102EF 抗体
zyxin 抗体
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