ZYX 产品
(Zyxin (ZYX))
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Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008].
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Featured ZYX Categories
ZYX 抗体
High quality antibodies with extensive validation data.
ZYX ELISA试剂盒
Reliable ELISA kits for a wide range of species.
ZYX 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ZYX 抗体
Product
Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
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Application
WB, ELISA, IF, IP, RNAi
Validations
- (2)
- (6)
Cat. No.
ABIN563471
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN521634
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
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- (5)
Cat. No.
ABIN6266149
Quantity
100 μL
Datasheet
Datasheet
Recommended ZYX ELISA试剂盒
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Reactivity
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Cat. No.
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Human
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Cat. No.
ABIN6975027
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96 tests
Datasheet
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Reactivity
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Analytical Method
Quantitative Sandwich ELISA
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Cat. No.
ABIN6960598
Quantity
96 tests
Datasheet
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Reactivity
Mouse
Analytical Method
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ABIN1168973
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96 tests
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Recommended ZYX 蛋白
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Reactivity
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Source
Escherichia coli (E. coli)
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- (1)
Cat. No.
ABIN7125821
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
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Cat. No.
ABIN1326572
Quantity
10 μg
Datasheet
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Reactivity
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Insect Cells
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Cat. No.
ABIN3076305
Quantity
1 mg
Datasheet
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Latest Publications for our ZYX Products
: "Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin." in: Scientific reports, Vol. 6, pp. 23258, (2016) (PubMed).: "NBR1 enables autophagy-dependent focal adhesion turnover." in: The Journal of cell biology, Vol. 212, Issue 5, pp. 577-90, (2016) (PubMed).
: "α-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation." in: PLoS ONE, Vol. 10, Issue 4, pp. e0120616, (2015) (PubMed).
: "Cell shape-dependent early responses of fibroblasts to cyclic strain." in: Biochimica et biophysica acta, Vol. 1833, Issue 12, pp. 3415-25, (2013) (PubMed).
: "Zyxin is a transforming growth factor-? (TGF-?)/Smad3 target gene that regulates lung cancer cell motility via integrin ?5?1." in: The Journal of biological chemistry, Vol. 287, Issue 37, pp. 31393-405, (2012) (PubMed).
: "Cell-penetrating peptides with intracellular actin-remodeling activity in malignant fibroblasts." in: The Journal of biological chemistry, Vol. 285, Issue 10, pp. 7712-21, (2010) (PubMed).
: "Domain analysis of alpha-actinin reveals new aspects of its association with F-actin during cytokinesis." in: Experimental cell research, Vol. 316, Issue 12, pp. 1925-34, (2010) (PubMed).
: "Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis." in: Molecular biology of the cell, Vol. 20, Issue 13, pp. 3115-24, (2009) (PubMed).
: "mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes." in: American journal of physiology. Renal physiology, Vol. 296, Issue 2, pp. F418-26, (2009) (PubMed).
: "Targeted disruption of the mouse Lipoma Preferred Partner gene." in: Biochemical and biophysical research communications, Vol. 379, Issue 2, pp. 368-73, (2009) (PubMed).
Synonyms and alternative names related to ZYX
Zyxin (zyx-1), Zyxin (Zyx), zyxin (zyx), zyxin (ZYX), zyxin (EDI_201420), zyxin (Zyx), zyxin S homeolog (zyx.S), 9530098H06Rik, BcDNA:LD06023, CG32018, DLim-1, Dmel\\CG32018, DmLIM-1, ESP-2, HED-2, lim, Lim102EF, MGC145270, R75157, zgc:171680, ZYX, zyx, ZYX102, Zyx102, zyx102, Zyx102EF, zyxinProtein level used designations for ZYX
- ZYXin family member (zyx-1)
- CG32018-PA
- CG32018-PB
- CG32018-PG
- CG32018-PH
- Zyx-PA
- Zyx-PB
- Zyx-PG
- Zyx-PH
- Zyx102EF
- zyxin
- hypothetical protein LOC779718
- zyxin-2
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