XRCC6 抗体
(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008].
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141 results
XRCC6
适用: 人, 小鼠, 猴, 非洲爪蟾, Hamster
WB, IF, IP, IHC (fp)
宿主: 小鼠
Monoclonal
N3H10
unconjugated
1 reference
Latest Publications for our XRCC6 抗体
: "Sp1-independent downregulation of NHEJ in response to BER deficiency." in: DNA repair, Vol. 86, pp. 102740, (2020) (PubMed).: "System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection. ..." in: Molecular cell, (2019) (PubMed).
: "Inhibition of Ku70 in a high-glucose environment aggravates bupivacaine-induced dorsal root ganglion neurotoxicity." in: Toxicology letters, Vol. 318, pp. 104-113, (2019) (PubMed).
: "Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability." in: Journal of cell science, Vol. 131, Issue 12, (2018) (PubMed).
: "Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes." in: Nature communications, Vol. 7, pp. 13049, (2018) (PubMed).
: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).
: "Immortalized myogenic cells from congenital muscular dystrophy type1A patients recapitulate aberrant caspase activation in pathogenesis: a new tool for MDC1A research." in: Skeletal muscle, Vol. 3, Issue 1, pp. 28, (2014) (PubMed).
: "Negative regulation of Toll-like receptor-4 signaling through the binding of glycosylphosphatidylinositol-anchored glycoprotein, CD14, with the sialic acid-binding lectin, CD33." in: The Journal of biological chemistry, Vol. 289, Issue 36, pp. 25341-50, (2014) (PubMed).
: "Phosphorothioate-modified CpG oligodeoxynucleotides mimic autoantigens and reveal a potential role for Toll-like receptor 9 in receptor revision." in: Immunology, Vol. 139, Issue 2, pp. 166-78, (2013) (PubMed).
: "DNA-PKcs expression predicts response to radiotherapy in prostate cancer." in: International journal of radiation oncology, biology, physics, Vol. 84, Issue 5, pp. 1179-85, (2012) (PubMed).
Aliases for XRCC6 抗体
X-ray repair cross complementing 6 (XRCC6) 抗体ATP-dependent DNA helicase II, 70 kDa subunit (Bm1_41430) 抗体
X-ray repair complementing defective repair in Chinese hamster cells 6 L homeolog (xrcc6.L) 抗体
X-ray repair complementing defective repair in Chinese hamster cells 6 (Xrcc6) 抗体
X-ray repair cross complementing 6 (Xrcc6) 抗体
X-ray repair complementing defective repair in Chinese hamster cells 6 (XRCC6) 抗体
70kDa 抗体
CTC75 抗体
CTCBF 抗体
G22P1 抗体
G22p1 抗体
KU70 抗体
Ku70 抗体
Kup70 抗体
ML8 抗体
TLAA 抗体
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