XAGE1B/GAGED2 产品
(X Antigen Family, Member 1B (XAGE1B))
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This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. The protein encoded by this gene contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene, in addition to alternative transcription start sites, results in multiple transcript variants. [provided by RefSeq, Jan 2010].
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Synonyms and alternative names related to XAGE1B/GAGED2
X antigen family member 1B (XAGE1B), CT12.1, CT12.1B, CTP9, GAGED2, XAGE-1Protein level used designations for XAGE1B/GAGED2
- G antigen family D member 2
- X antigen family member 1
- cancer/testis antigen 12.1
- cancer/testis antigen family 12, member 1b
- cancer/testis associated protein
- protein XAGE-1
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