XAGE1 抗体
(X Antigen Family, Member 1A (XAGE1A))
This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. The protein encoded by this gene contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene, in addition to alternative transcription start sites, results in multiple transcript variants. [provided by RefSeq, Jan 2010].
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Latest Publications for our XAGE1 抗体
: "Characterization of overlapping XAGE-1 transcripts encoding a cancer testis antigen expressed in lung, breast, and other types of cancers." in: Molecular cancer therapeutics, Vol. 1, Issue 7, pp. 441-50, (2002) (PubMed).: "XAGE-1, a new gene that is frequently expressed in Ewing's sarcoma." in: Cancer research, Vol. 60, Issue 17, pp. 4752-5, (2000) (PubMed).
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