电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

WWP1 抗体

(WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1\; the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF.

26 results

WWP1 适用: 人 WB, ELISA, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A7 unconjugated
Pubmed 6 references
产品编号 ABIN564794
 
WWP1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7245725
 
WWP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B7 unconjugated
产品编号 ABIN524448
 
WWP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6266055
 
WWP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7271394
 
WWP1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7261223
 
WWP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
产品编号 ABIN564793
 
WWP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN524446
 
WWP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A7 unconjugated
产品编号 ABIN466175
 
WWP1 适用: 人, 小鼠, Cow, 犬, 豚鼠, 兔, Bat WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6743154
 
WWP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN634475
 
WWP1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2774928
 
WWP1 适用: 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN720910
 
WWP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IP, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7120866
 
WWP1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7452169
 
WWP1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7452554
 
WWP1 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7467665
 
WWP1 适用: 人 宿主: 兔 Polyclonal Alexa Fluor 555
产品编号 ABIN6887559
 
WWP1 适用: 人 宿主: 兔 Polyclonal Alexa Fluor 680
产品编号 ABIN6903622
 
WWP1 适用: 人 宿主: 兔 Polyclonal Alexa Fluor 488
产品编号 ABIN6815180
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • Immunofluorescence (IF)
    • Immunohistochemistry (IHC)
    • Immunoprecipitation (IP)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunocytochemistry (ICC)
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 适用
    • Human
    • Mouse
    • Rat
    • Cow
    • Dog
    • Guinea Pig
    • Rabbit
    • Bat
    • Horse
    • Pig
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • 1A7
    • 2B7
  • 抗原表位
    • AA 152-260
    • N-Term
    • AA 1-922
    • AA 152-261
    • AA 1-260
    • AA 200-250
    • AA 21-120
    • AA 300-350
    • Internal Region
  • 标记
    • 非结合性
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • Biotin
  • 抗体亚型
    • IgG
    • IgG2a kappa
    • IgG1
    • IgG2a
  • Format
    • Liquid
    • Lyophilized
  • Supplier
    • antibodies-online
    • Signalway
    • USBio
    • Aviva Systems Biology

Latest Publications for our WWP1 抗体

Cho, Yoo, Yoon, Yoon: "β-dystroglycan is regulated by a balance between WWP1-mediated degradation and protection from WWP1 by dystrophin and utrophin." in: Biochimica et biophysica acta. Molecular basis of disease, Vol. 1864, Issue 6 Pt A, pp. 2199-2213, (2018) (PubMed).

Basheer, Harris, Mentrup, Abreha, Thames, Lea, Swing, Copeland, Jenkins, Price, Matesic: "Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis." in: Journal of molecular and cellular cardiology, Vol. 88, pp. 1-13, (2015) (PubMed).

Cheng, Cao, Yuan, Li, Tong: "Knockdown of WWP1 inhibits growth and induces apoptosis in hepatoma carcinoma cells through the activation of caspase3 and p53." in: Biochemical and biophysical research communications, Vol. 448, Issue 3, pp. 248-54, (2014) (PubMed).

Chaudhary, Maddika: "WWP2-WWP1 ubiquitin ligase complex coordinated by PPM1G maintains the balance between cellular p73 and ?Np73 levels." in: Molecular and cellular biology, Vol. 34, Issue 19, pp. 3754-64, (2014) (PubMed).

Subik, Shu, Wu, Liang, Hicks, Boyce, Schiffhauer, Chen, Chen, Tang, Xing: "The ubiquitin E3 ligase WWP1 decreases CXCL12-mediated MDA231 breast cancer cell migration and bone metastasis." in: Bone, Vol. 50, Issue 4, pp. 813-23, (2012) (PubMed).

Cao, Xue, Han, Ma, Chen, Tong: "WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) delays cellular senescence by promoting p27(Kip1) degradation in human diploid fibroblasts." in: The Journal of biological chemistry, Vol. 286, Issue 38, pp. 33447-56, (2011) (PubMed).

Peschiaroli, Scialpi, Bernassola, El Sherbini, Melino: "The E3 ubiquitin ligase WWP1 regulates ?Np63-dependent transcription through Lys63 linkages." in: Biochemical and biophysical research communications, Vol. 402, Issue 2, pp. 425-30, (2010) (PubMed).

Edwards, Clowes, Tsang, Connell, Sanderson, Luzio, Reid: "Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5." in: The Biochemical journal, Vol. 423, Issue 1, pp. 31-9, (2009) (PubMed).

Aliases for WWP1 抗体

WW domain containing E3 ubiquitin protein ligase 1 (WWP1) 抗体
WW domain containing E3 ubiquitin protein ligase 1 (Wwp1) 抗体
WW domain containing E3 ubiquitin protein ligase 1 (wwp1) 抗体
8030445B08Rik 抗体
AIP5 抗体
aip5 抗体
hSDRP1 抗体
hsdrp1 抗体
SDRP1 抗体
Tiul1 抗体
tiul1 抗体
WWP1 抗体
You are here:
Chat with us!