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WWP1 抗体

WWP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IP, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7120866
发货至: 中国
  • 抗原 See all WWP1 抗体
    WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
    适用
    • 23
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 19
    • 5
    克隆类型
    • 20
    • 4
    多克隆
    标记
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WWP1 antibody is un-conjugated
    应用范围
    • 14
    • 7
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    WW domain containing E3 ubiquitin protein ligase 1
    亚型
    IgG
    Top Product
    Discover our top product WWP1 Primary Antibody
  • 应用备注
    WB: 1:200-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
    别名
    WWP1 (WWP1 产品)
    别名
    AIP5 antibody, Tiul1 antibody, hSDRP1 antibody, 8030445B08Rik antibody, SDRP1 antibody, WWP1 antibody, aip5 antibody, tiul1 antibody, hsdrp1 antibody, WW domain containing E3 ubiquitin protein ligase 1 antibody, WWP1 antibody, Wwp1 antibody, wwp1 antibody
    背景
    Synonyms:AIP5, DKFZp434D2111, hSDRP1, Tiul1, WW domain containing protein 1, WWP1 Background:E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1, the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF.
    分子量
    95 kDa
    基因ID
    11059
    UniProt
    Q9H0M0
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