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WWOX 抗体

(WW Domain Containing Oxidoreductase (WWOX))
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90% identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008].

68 results :

WWOX 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7175871
 
WWOX 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
Pubmed 1 reference
产品编号 ABIN670551
 
WWOX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5693294
 
WWOX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5708495
 
WWOX 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7138983
 
WWOX 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
产品编号 ABIN526913
 
WWOX 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6259234
 
WWOX 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6150272
 
WWOX 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1804276
 
WWOX 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7256280
 
WWOX 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6747534
 
WWOX 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN926732
 
WWOX 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1532116
 
WWOX 适用: 人, 小鼠, 小鸡, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7303028
 
WWOX 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7189077
 
WWOX 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6287556
 
WWOX 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6280592
 
WWOX 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7175874
 
WWOX 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7175873
 
WWOX 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7175872
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • Immunohistochemistry (IHC)
    • Immunofluorescence (IF)
    • Immunoprecipitation (IP)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunocytochemistry (ICC)
    • Flow Cytometry (FACS)
    • Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    • Enzyme Immunoassay (EIA)
    • Immunochromatography (IC)
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 适用
    • Human
    • Mouse
    • Rat
    • Cow
    • Guinea Pig
    • Horse
    • Chicken
    • Dog
    • Monkey
    • Pig
    • Rabbit
    • Zebrafish (Danio rerio)
  • 论文引用
  • 图像
  • Preservative free only
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
    • Sheep
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • 3D10
    • R02-0E3R02-0E3
  • 抗原表位
    • pTyr33
    • AA 369-396
    • C-Term
    • AA 1-180
    • N-Term
    • AA 89-107
    • AA 1-189
    • AA 1-245
    • AA 36-126
    • AA 368-396
    • AA 75-125
    • AA 1-120
    • AA 1-186
    • AA 1-50
    • AA 1-80
    • AA 10-90
    • AA 18-67
    • AA 364-414
    • AA 5-100
    • AA 95-144
    • Ala7
  • 标记
    • 非结合性
    • Biotin
    • FITC
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • HRP
    • APC
    • PE
  • 抗体亚型
    • IgG
    • Ig Fraction
    • IgG1
  • 蛋白类型
    • Recombinant Antibody
  • Format
    • Liquid
    • Lyophilized
  • Supplier
    • antibodies-online
    • Signalway
    • USBio
    • Abbexa
    • Assay Biotechnology Company, Inc.
    • Boster Bio
    • Cohesion Biosciences
    • Acris
    • Angio-Proteomie
    • Aviva Systems Biology
    • Biomatik
    • Covalab
    • NSJ Bioreagents
    • ProSci
    • QED Bioscience
    • RayBiotech

Latest Publications for our WWOX 抗体

Henssen, Koche, Zhuang, Jiang, Reed, Eisenberg, Still, MacArthur, Rodríguez-Fos, Gonzalez, Puiggròs, Blackford, Mason, de Stanchina, Gönen, Emde, Shah, Arora, Reeves, Socci, Perlman, Antonescu et al.: "PGBD5 promotes site-specific oncogenic mutations in human tumors. ..." in: Nature genetics, Vol. 49, Issue 7, pp. 1005-1014, (2017) (PubMed).

Zhang, Zhang, Cong, Zhang: "The ectopic expression of BRCA1 is associated with genesis, progression, and prognosis of breast cancer in young patients." in: Diagnostic pathology, Vol. 7, pp. 181, (2013) (PubMed).

Fabbri, Iliopoulos, Trapasso, Aqeilan, Cimmino, Zanesi, Yendamuri, Han, Amadori, Huebner, Croce: "WWOX gene restoration prevents lung cancer growth in vitro and in vivo." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 43, pp. 15611-6, (2005) (PubMed).

Park, Ludes-Meyers, Zimonjic, Durkin, Popescu, Aldaz: "Frequent downregulation and loss of WWOX gene expression in human hepatocellular carcinoma." in: British journal of cancer, Vol. 91, Issue 4, pp. 753-9, (2004) (PubMed).

Chang, Doherty, Ensign: "JNK1 physically interacts with WW domain-containing oxidoreductase (WOX1) and inhibits WOX1-mediated apoptosis." in: The Journal of biological chemistry, Vol. 278, Issue 11, pp. 9195-202, (2003) (PubMed).

Bednarek, Keck-Waggoner, Daniel, Laflin, Bergsagel, Kiguchi, Brenner, Aldaz: "WWOX, the FRA16D gene, behaves as a suppressor of tumor growth." in: Cancer research, Vol. 61, Issue 22, pp. 8068-73, (2001) (PubMed).

Paige, Taylor, Taylor, Hillier, Farrington, Scott, Porteous, Smyth, Gabra, Watson: "WWOX: a candidate tumor suppressor gene involved in multiple tumor types." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 20, pp. 11417-22, (2001) (PubMed).

Bednarek, Laflin, Daniel, Liao, Hawkins, Aldaz: "WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer." in: Cancer research, Vol. 60, Issue 8, pp. 2140-5, (2000) (PubMed).

Ried, Finnis, Hobson, Mangelsdorf, Dayan, Nancarrow, Woollatt, Kremmidiotis, Gardner, Venter, Baker, Richards: "Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells." in: Human molecular genetics, Vol. 9, Issue 11, pp. 1651-63, (2000) (PubMed).

Aliases for WWOX 抗体

WW domain containing oxidoreductase (Wwox) 抗体
WW domain-containing oxidoreductase (LOC411815) 抗体
WW domain containing oxidoreductase (WWOX) 抗体
WW domain-containing oxidoreductase (CpipJ_CPIJ004939) 抗体
WW domain-containing oxidoreductase (MCYG_01584) 抗体
WW domain-containing oxidoreductase (VDBG_05631) 抗体
WW domain-containing oxidoreductase (VDBG_01326) 抗体
WW domain-containing oxidoreductase (VDBG_06753) 抗体
WW domain-containing oxidoreductase (Tsp_03967) 抗体
WW domain-containing oxidoreductase (LOC100284583) 抗体
WW domain containing oxidoreductase (wwox) 抗体
WW domain-containing oxidoreductase (Wwox) 抗体
5330426P09Rik 抗体
9030416C10Rik 抗体
anon-EST:Posey177 抗体
CG7221 抗体
D16S432E 抗体
Dmel\\CG7221 抗体
DmWWOX 抗体
FOR 抗体
FRA16D 抗体
GB11795 抗体
HHCMA56 抗体
PRO0128 抗体
SDR41C1 抗体
WOX1 抗体
WWOX 抗体
zgc:55975 抗体
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