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USP7 蛋白

(Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))
Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6 (By similarity).
USP7 Protein (AA 214-521) (His tag) USP7 Protein (AA 214-521) (His tag) USP7 Protein (AA 214-521) (His tag) (ABIN7125598)

USP7 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

USP7 Protein (AA 13-110) (GST tag) USP7 Protein (AA 13-110) (GST tag) USP7 Protein (AA 13-110) (GST tag) (ABIN1324846)

USP7 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

USP7 Protein (AA 1-1102) (His tag) USP7 Protein (AA 1-1102) (His tag) USP7 Protein (AA 1-1102) (His tag) (ABIN3096200)

Crystallography grade USP7 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

USP7 蛋白 by Grade

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USP7 蛋白 by Origin

Find USP7 蛋白 for a variety of species such as anti-Human USP7. The species listed below are among those available. Click on a link to go to the corresponding products.

USP7 蛋白 by Source

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USP7 蛋白 by 蛋白类型

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USP7 蛋白 by 应用范围

Find USP7 蛋白 validated for a specific application such as WB, ELISA, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular USP7 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125598
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324846
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3096200
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7416877
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
Cat. No. ABIN7198567
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
Cat. No. ABIN7198568
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2735144
Quantity 20 μg
Datasheet Datasheet

Aliases for USP7 蛋白

Ubiquitin-specific protease 7 (Usp7) 蛋白
ubiquitin carboxyl-terminal hydrolase 7 (LOC100201254) 蛋白
ubiquitin specific peptidase 7 (USP7) 蛋白
ubiquitin specific peptidase 7 (Usp7) 蛋白
2210010O09Rik 蛋白
AA409944 蛋白
AA617399 蛋白
AU019296 蛋白
AW548146 蛋白
C80752 蛋白
CG1490 蛋白
Dmel\\CG1490 蛋白
Hausp 蛋白
HAUSP 蛋白
TEF1 蛋白
UBP 蛋白
USP7 蛋白
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