USP20 蛋白
(Ubiquitin Specific Peptidase 20 (USP20))
This gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel-Lindau disease) protein E3 ubiquitin ligase complex. In addition to being ubiquitinated by the VHL-E3 ligase complex, this enzyme deubiquitinates hypoxia-inducible factor (HIF)-1 alpha and thereby causes increased expression of HIF-1alpha targeted genes which play a role in angiogenesis, glucose metabolism, cell proliferation and metastasis. The enzyme encoded by this gene also regulates G-protein coupled receptor signaling by mediating the deubiquitination of beta-2 adrenergic receptor (ADRB2). This enzyme is a ubiquitously expressed thiolester hydrolase. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jan 2013].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| USP20 Protein (AA 1-913) (GST tag) | 人 | 小麦胚 |
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| USP20 Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| USP20 Protein (GST tag) | 人 | Baculovirus infected Insect Cells |
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| USP20 Protein (AA 1-914) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| USP20 Protein (AA 682-914) (His-IF2DI Tag) | 人 | 大肠杆菌（E. Coli） |
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| USP20 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| USP20 Protein (AA 781-914) (His tag) | 人 | Bacteria |
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| USP20 Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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Protein
- AP (Affinity Purification: 所列应用)
- AA (Antibody Array: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
1 reference - 宿主
- 人
- 宿主
- 小麦胚
- 蛋白类型
- Recombinant
Protein
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- WB (Western Blotting: 所列应用)
- AcA (Activity Assay: 所列应用)
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 生物活性
- Active
Protein
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Latest Publications for our USP20 蛋白
: "Ubiquitin-specific peptidase 20 regulates Rad17 stability, checkpoint kinase 1 phosphorylation and DNA repair by homologous recombination." in: The Journal of biological chemistry, Vol. 289, Issue 33, pp. 22739-48, (2014) (PubMed).
Aliases for USP20 蛋白
universal stress protein (RR_RS15875) 蛋白ubiquitin specific peptidase 20 (USP20) 蛋白
ubiquitin specific peptidase 20 (usp20) 蛋白
ubiquitin specific peptidase 20 (Usp20) 蛋白
ubiquitin specific peptidase 20 L homeolog (usp20.L) 蛋白
1700055M05Rik 蛋白
AI467231 蛋白
hVDU2 蛋白
im:7151955 蛋白
lsfr3a 蛋白
LSFR3A 蛋白
USP20 蛋白
vdu2 蛋白
VDU2 蛋白
Vdu2 蛋白
zgc:63661 蛋白
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