This gene encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
custom-made
USP16
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Frangini, Sjöberg, Roman-Trufero, Dharmalingam, Haberle, Bartke, Lenhard, Malumbres, Vidal, Dillon: "The aurora B kinase and the polycomb protein ring1B combine to regulate active promoters in quiescent lymphocytes." in: Molecular cell, Vol. 51, Issue 5, pp. 647-61, (2013) (PubMed).
Aliases for USP16 蛋白
universal stress protein (usp16) 蛋白 ubiquitin specific peptidase 16 (USP16) 蛋白 ubiquitin specific peptidase 16 (usp16) 蛋白 ubiquitin specific peptidase 16 (Usp16) 蛋白 ubiquitin specific peptidase 16 L homeolog (usp16.L) 蛋白 1200004E02Rik 蛋白 2810483I07Rik 蛋白 6330514E22Rik 蛋白 si:ch211-238e22.5 蛋白 si:dkey-121n8.2 蛋白 ubp-m 蛋白 UBP-M 蛋白 UBPM 蛋白 USP16 蛋白 wu:fc76b02 蛋白 wu:fc76b08 蛋白