USP7 抗体
(Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))
Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6 (By similarity).
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| Recombinant USP7 抗体 (Alexa Fluor 405) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant USP7 抗体 (Alexa Fluor 350) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant USP7 抗体 (Alexa Fluor 750) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant USP7 抗体 (Biotin) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant USP7 抗体 (Alexa Fluor 555) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant USP7 抗体 (Alexa Fluor 488) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant USP7 抗体 (Alexa Fluor 647) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant USP7 抗体 (Alexa Fluor 680) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant USP7 抗体 (Alexa Fluor 594) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| USP7 抗体 (Alexa Fluor 750) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| USP7 抗体 (Alexa Fluor 594) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| USP7 抗体 (Alexa Fluor 488) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| Recombinant USP7 抗体 (Biotin) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant USP7 抗体 (Alexa Fluor 555) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant USP7 抗体 (Alexa Fluor 594) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant USP7 抗体 (Alexa Fluor 647) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant USP7 抗体 (Alexa Fluor 680) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant USP7 抗体 (Alexa Fluor 405) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant USP7 抗体 (Alexa Fluor 488) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant USP7 抗体 (Alexa Fluor 750) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 405
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 350
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 750
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Biotin
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 555
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 488
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 647
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 680
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 594
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- S02-6B8
- 标记
- Biotin
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- S02-6B8
- 标记
- Alexa Fluor 555
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- S02-6B8
- 标记
- Alexa Fluor 594
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 647
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- S02-6B8
- 标记
- Alexa Fluor 680
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- S02-6B8
- 标记
- Alexa Fluor 405
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- S02-6B8
- 标记
- Alexa Fluor 488
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- S02-6B8
- 标记
- Alexa Fluor 750
- 蛋白类型
- Recombinant Antibody
Latest Publications for our USP7 抗体
: "Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation." in: Biology of reproduction, Vol. 94, Issue 2, pp. 31, (2016) (PubMed).
: "The stress-responsive gene ATF3 regulates the histone acetyltransferase Tip60." in: Nature communications, Vol. 6, pp. 6752, (2015) (PubMed).
: "Adenovirus E4-ORF3 Targets PIAS3 and Together with E1B-55K Remodels SUMO Interactions in the Nucleus and at Virus Genome Replication Domains." in: Journal of virology, Vol. 89, Issue 20, pp. 10260-72, (2015) (PubMed).
: "Expression of DNA repair and replication genes in non-small cell lung cancer (NSCLC): a role for thymidylate synthetase (TYMS)." in: BMC cancer, Vol. 12, Issue 1, pp. 342, (2012) (PubMed).
: "Alternate splicing of the p53 inhibitor HDMX offers a superior prognostic biomarker than p53 mutation in human cancer." in: Cancer research, Vol. 72, Issue 16, pp. 4074-84, (2012) (PubMed).
: "Microarray-based identification of age-dependent differences in gene expression of human dermal fibroblasts." in: Mechanisms of ageing and development, Vol. 133, Issue 7, pp. 498-507, (2012) (PubMed).
: "The RNA-binding E3 ubiquitin ligase MEX-3C links ubiquitination with MHC-I mRNA degradation." in: The EMBO journal, Vol. 31, Issue 17, pp. 3596-606, (2012) (PubMed).
: "KIAA1530 protein is recruited by Cockayne syndrome complementation group protein A (CSA) to participate in transcription-coupled repair (TCR)." in: The Journal of biological chemistry, Vol. 287, Issue 42, pp. 35118-26, (2012) (PubMed).
: "High levels of Hdmx promote cell growth in a subset of uveal melanomas." in: American journal of cancer research, Vol. 2, Issue 5, pp. 492-507, (2012) (PubMed).
: "UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair." in: Nature genetics, Vol. 44, Issue 5, pp. 598-602, (2012) (PubMed).
: "The stress-responsive gene ATF3 regulates the histone acetyltransferase Tip60." in: Nature communications, Vol. 6, pp. 6752, (2015) (PubMed).
: "Adenovirus E4-ORF3 Targets PIAS3 and Together with E1B-55K Remodels SUMO Interactions in the Nucleus and at Virus Genome Replication Domains." in: Journal of virology, Vol. 89, Issue 20, pp. 10260-72, (2015) (PubMed).
: "Expression of DNA repair and replication genes in non-small cell lung cancer (NSCLC): a role for thymidylate synthetase (TYMS)." in: BMC cancer, Vol. 12, Issue 1, pp. 342, (2012) (PubMed).
: "Alternate splicing of the p53 inhibitor HDMX offers a superior prognostic biomarker than p53 mutation in human cancer." in: Cancer research, Vol. 72, Issue 16, pp. 4074-84, (2012) (PubMed).
: "Microarray-based identification of age-dependent differences in gene expression of human dermal fibroblasts." in: Mechanisms of ageing and development, Vol. 133, Issue 7, pp. 498-507, (2012) (PubMed).
: "The RNA-binding E3 ubiquitin ligase MEX-3C links ubiquitination with MHC-I mRNA degradation." in: The EMBO journal, Vol. 31, Issue 17, pp. 3596-606, (2012) (PubMed).
: "KIAA1530 protein is recruited by Cockayne syndrome complementation group protein A (CSA) to participate in transcription-coupled repair (TCR)." in: The Journal of biological chemistry, Vol. 287, Issue 42, pp. 35118-26, (2012) (PubMed).
: "High levels of Hdmx promote cell growth in a subset of uveal melanomas." in: American journal of cancer research, Vol. 2, Issue 5, pp. 492-507, (2012) (PubMed).
: "UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair." in: Nature genetics, Vol. 44, Issue 5, pp. 598-602, (2012) (PubMed).
Aliases for USP7 抗体
Ubiquitin-specific protease 7 (Usp7) 抗体ubiquitin carboxyl-terminal hydrolase 7 (LOC100201254) 抗体
ubiquitin specific peptidase 7 (USP7) 抗体
ubiquitin specific peptidase 7 (Usp7) 抗体
2210010O09Rik 抗体
AA409944 抗体
AA617399 抗体
AU019296 抗体
AW548146 抗体
C80752 抗体
CG1490 抗体
Dmel\\CG1490 抗体
Hausp 抗体
HAUSP 抗体
TEF1 抗体
UBP 抗体
USP7 抗体
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