UGT1A4 产品
(UDP Glucuronosyltransferase 1 Family, Polypeptide A4 (UGT1A4))
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This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins. [provided by RefSeq, Jul 2008].
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Featured UGT1A4 Categories
Recommended UGT1A4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN6749736
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN6265875
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7192987
Quantity
100 μL
Datasheet
Datasheet
Recommended UGT1A4 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324577
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3113167
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2734991
Quantity
20 μg
Datasheet
Datasheet
Synonyms and alternative names related to UGT1A4
UDP glucuronosyltransferase family 1 member A4 (UGT1A4), UDP-glucuronosyltransferase 1-4 (UGT1-4), HUG-BR2, UDPGT, UDPGT 1-4, UGT-1D, UGT1, UGT1-04, UGT1.4, UGT1A4, UGT1DProtein level used designations for UGT1A4
- UDP glycosyltransferase 1 family, polypeptide A4
- UDP-glucuronosyltransferase 1-4
- UDP-glucuronosyltransferase 1-D
- UDP-glucuronosyltransferase 1A4
- bilirubin UDP-glucuronosyltransferase isozyme 2
- bilirubin-specific UDPGT isozyme 2
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