UFD1L 抗体
(Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Jun 2009].
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Latest Publications for our UFD1L 抗体
: "VCP cooperates with UBXD1 to degrade mitochondrial outer membrane protein MCL1 in model of Huntington's disease." in: Biochimica et biophysica acta, Vol. 1863, Issue 2, pp. 552-559, (2016) (PubMed).: "SVIP is a novel VCP/p97-interacting protein whose expression causes cell vacuolation." in: Molecular biology of the cell, Vol. 14, Issue 1, pp. 262-73, (2003) (PubMed).
: "A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways." in: The EMBO journal, Vol. 19, Issue 10, pp. 2181-92, (2000) (PubMed).
: "A molecular pathway revealing a genetic basis for human cardiac and craniofacial defects." in: Science (New York, N.Y.), Vol. 283, Issue 5405, pp. 1158-61, (1999) (PubMed).
: "UFD1L, a developmentally expressed ubiquitination gene, is deleted in CATCH 22 syndrome." in: Human molecular genetics, Vol. 6, Issue 2, pp. 259-65, (1997) (PubMed).
Aliases for UFD1L 抗体
ubiquitin recognition factor in ER associated degradation 1 (UFD1) 抗体ubiquitin recognition factor in ER-associated degradation 1 (Ufd1) 抗体
ubiquitin recognition factor in ER associated degradation 1 (Ufd1) 抗体
ubiquitin fusion degradation 1 like (yeast) (UFD1L) 抗体
ubiquitin recognition factor in ER associated degradation 1 S homeolog (ufd1.S) 抗体
ubiquitin recognition factor in ER associated degradation 1 (ufd1l) 抗体
ubiquitin recognition factor in ER associated degradation 1 (ufd1) 抗体
ubiquitin fusion degradation protein 1 homolog (EHI_125920) 抗体
ubiquitin fusion degradation protein 1 homolog (LOC100166745) 抗体
ubiquitin fusion degradation protein 1 homolog (LOC100635687) 抗体
ubiquitin fusion degradation protein 1 homolog (LOC100648660) 抗体
Ubiquitin Fusion Degradation (yeast UFD homolog) (ufd-1) 抗体
UFD1 抗体
Ufd1 抗体
ufd1 抗体
Ufd1l 抗体
wu:fc55f04 抗体
zgc:92341 抗体
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