UFD1L 抗体
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北京 101111
Quick Overview for UFD1L 抗体 (ABIN7232030)
抗原
See all UFD1L 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-UFD1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of UFD1 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human UFD1 protein
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亚型
- IgG
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anti-Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) (AA 208-307) antibody
UFD1L 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 4F11A4 unconjugated
anti-Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) (AA 208-307) antibodyUFD1L 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2A6F3 unconjugated
anti-Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) (full length) antibodyUFD1L 适用: 人, 小鼠 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) (Internal Region) antibodyUFD1L 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) (AA 1-307) antibodyUFD1L 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) (AA 1-307) antibodyUFD1L 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) antibodyKD Validated UFD1L 适用: 人 WB 宿主: 兔 Monoclonal 25GB7980 unconjugated Recombinant Antibody
anti-Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) (AA 161-210) antibodyUFD1L 适用: 人, 大鼠, 犬, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) antibodyUFD1L 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) (AA 175-225) antibodyUFD1L 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
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别名
- UFD1
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背景
- Ubiquitin recognition factor in ER-associated degradation protein 1, Ubiquitin fusion degradation protein 1, UB fusion protein 1UFD1 (Ubiquitin Recognition Factor In ER Associated Degradation 1) is a Protein Coding gene. Diseases associated with UFD1 include Velocardiofacial Syndrome and Inclusion Body Myopathy With Paget Disease Of Bone And Frontotemporal Dementia. Among its related pathways are Protein processing in endoplasmic reticulum and Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template. The protein encoded by UFD1 forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in UFD1 have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.
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分子量
- 33kD
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基因ID
- 7353
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UniProt
- Q92890
抗原
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