UBR1 抗体
(Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))
The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq, Jul 2008].
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Latest Publications for our UBR1 抗体
: "Lack of association of genetic variation in chromosome region 15q14-22.1 with type 2 diabetes in a Japanese population." in: BMC medical genetics, Vol. 9, pp. 22, (2008) (PubMed).: "Roles of STAT3/SOCS3 pathway in regulating the visual function and ubiquitin-proteasome-dependent degradation of rhodopsin during retinal inflammation." in: The Journal of biological chemistry, Vol. 283, Issue 36, pp. 24561-70, (2008) (PubMed).
: "Johanson-Blizzard syndrome with mild phenotypic features confirmed by UBR1 gene testing." in: World journal of gastroenterology : WJG, Vol. 14, Issue 44, pp. 6863-6, (2008) (PubMed).
: "Thiazolidinediones modulate the expression of beta-catenin and other cell-cycle regulatory proteins by targeting the F-box proteins of Skp1-Cul1-F-box protein E3 ubiquitin ligase independently of..." in: Molecular pharmacology, Vol. 72, Issue 3, pp. 725-33, (2007) (PubMed).
Aliases for UBR1 抗体
Ubr1 ubiquitin ligase (Ubr1) 抗体ubiquitin protein ligase E3 component n-recognin 1 (ubr1) 抗体
ubiquitin protein ligase E3 component n-recognin 1 (UBR1) 抗体
E3 ubiquitin-protein ligase ubr-1 (ubr-1) 抗体
ubiquitin protein ligase E3 component n-recognin 1 (Ubr1) 抗体
AI504731 抗体
Dmel\\CG9086 抗体
JBS 抗体
RGD1562326 抗体
Ubr1 抗体
UBR1 抗体
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