UBR1 抗体 (AA 790-870)
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北京 101111
Quick Overview for UBR1 抗体 (AA 790-870) (ABIN7217434)
抗原
See all UBR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 790-870
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原理
- Rabbit Anti-Ubr1 Polyclonal Antibody
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特异性
- Ubr1 Polyclonal Antibody detects endogenous levels of Ubr1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human Ubr1 at AA range: 790-870
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))
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别名
- Ubr1
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背景
- UBR1, E3 ubiquitin-protein ligase UBR1, N-recognin-1, Ubiquitin-protein ligase E3-alpha-1, Ubiquitin-protein ligase E3-alpha-IThe N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by UBR1, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. E3 ubiquitin-protein ligase UBR1 described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome.
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分子量
- 200kD
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基因ID
- 197131
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UniProt
- Q8IWV7
抗原
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