(Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A))
This gene encodes one of two family members belonging to the T-cell ubiquitin ligand (TULA) family. Both family members can negatively regulate T-cell signaling. This family member can facilitate growth factor withdrawal-induced apoptosis in T cells, which may occur via its interaction with AIF, an apoptosis-inducing factor. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011].
Kowanetz, Crosetto, Haglund, Schmidt, Heldin, Dikic: "Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases." in: The Journal of biological chemistry, Vol. 279, Issue 31, pp. 32786-95, (2004) (PubMed).
Aliases for UBASH3A 抗体
ubiquitin associated and SH3 domain containing A (UBASH3A) 抗体 ubiquitin associated and SH3 domain containing, A (Ubash3a) 抗体 5830413C03Rik 抗体 C330001M22 抗体 CLIP4 抗体 STS-2 抗体 Sts-2 抗体 TULA 抗体 TULA-1 抗体 UBASH3A 抗体