TYROBP 抗体
(TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010].
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73 results
TYROBP
适用: 人
宿主: 兔
Monoclonal
Alexa Fluor 680
Recombinant Antibody
TYROBP
适用: 人
宿主: 兔
Monoclonal
Alexa Fluor 555
Recombinant Antibody
Latest Publications for our TYROBP 抗体
: "Expansion and activation of distinct central memory T lymphocyte subsets in complex regional pain syndrome." in: Journal of neuroinflammation, Vol. 16, Issue 1, pp. 63, (2019) (PubMed).: "The female reproductive tract contains multiple innate sialic acid-binding immunoglobulin-like lectins (Siglecs) that facilitate sperm survival." in: The Journal of biological chemistry, Vol. 294, Issue 31, pp. 11910-11919, (2019) (PubMed).
: "CD33 modulates TREM2: convergence of Alzheimer loci." in: Nature neuroscience, Vol. 18, Issue 11, pp. 1556-8, (2016) (PubMed).
: "Th2-M2 immunity in lesions of muscular sarcoidosis and macrophagic myofasciitis." in: Neuropathology and applied neurobiology, Vol. 41, Issue 7, pp. 952-63, (2015) (PubMed).
: "The ITAM-bearing transmembrane adaptor DAP12 in lymphoid and myeloid cell function." in: Immunology today, Vol. 21, Issue 12, pp. 611-4, (2001) (PubMed).
: "Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts." in: Nature genetics, Vol. 25, Issue 3, pp. 357-61, (2000) (PubMed).
: "Combined natural killer cell and dendritic cell functional deficiency in KARAP/DAP12 loss-of-function mutant mice." in: Immunity, Vol. 13, Issue 3, pp. 355-64, (2000) (PubMed).
Aliases for TYROBP 抗体
TYRO protein tyrosine kinase binding protein (TYROBP) 抗体TYRO protein tyrosine kinase binding protein (tyrobp) 抗体
Tyro protein tyrosine kinase binding protein (Tyrobp) 抗体
TYRO protein tyrosine kinase binding protein (Tyrobp) 抗体
DAP12 抗体
dap12 抗体
Karap 抗体
KARAP 抗体
Ly83 抗体
PLOSL 抗体
TYROBP 抗体
tyrpbp 抗体
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