Twisted Gastrulation Homolog 1 蛋白
(Twisted Gastrulation Homolog 1 (TWSG1))
May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity).
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13 results :
TWSG1
宿主: 人
宿主: 小麦胚
Recombinant
WB, ELISA, AA, AP
1 image
1 reference
TWSG1
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
> 93 % as determined by SDS-PAGE
1 image
TWSG1
宿主: 人
宿主: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
WB, ELISA, SDS, Imm, AcA
Active
TWSG1
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 97 %
WB, SDS, Imm, PC
TWSG1
宿主: 人
宿主: 人细胞
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Latest Publications for our Twisted Gastrulation Homolog 1 蛋白
: "High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin." in: Nature medicine, Vol. 13, Issue 9, pp. 1096-101, (2007) (PubMed).Aliases for Twisted Gastrulation Homolog 1 蛋白
twisted gastrulation BMP signaling modulator 1 (TWSG1) 蛋白twisted gastrulation homolog 1 (Drosophila) (TWSG1) 蛋白
twisted gastrulation BMP signaling modulator 1 (Twsg1) 蛋白
twisted gastrulation BMP signaling modulator 1a (twsg1a) 蛋白
twisted gastrulation BMP signaling modulator 1 S homeolog (twsg1.S) 蛋白
twisted gastrulation BMP signaling modulator 1 L homeolog (twsg1.L) 蛋白
twisted gastrulation BMP signaling modulator 1b (twsg1b) 蛋白
1810013J15Rik 蛋白
9030422N06Rik 蛋白
AW552143 蛋白
D17Ertd403e 蛋白
DKFZp469J051 蛋白
fi23f01 蛋白
TSG 蛋白
Tsg 蛋白
tsg 蛋白
tsg1 蛋白
tsga 蛋白
tsgb 蛋白
Twg 蛋白
twsg 蛋白
TWSG1 蛋白
twsg1 蛋白
wu:fi23f01 蛋白
ztsg1 蛋白
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