This gene encodes a member of the tumor protein D52 (TPD52) family. The encoded protein contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed, but the full-length nature of some variants has not yet been determined. [provided by RefSeq, Jul 2008].
Boutros, Bailey, Wilson, Byrne: "Alternative splicing as a mechanism for regulating 14-3-3 binding: interactions between hD53 (TPD52L1) and 14-3-3 proteins." in: Journal of molecular biology, Vol. 332, Issue 3, pp. 675-87, (2003) (PubMed).
Aliases for TPD52L1 抗体
tumor protein D52-like 1 (Tpd52l1) 抗体 tumor protein D52 like 1 L homeolog (tpd52l1.L) 抗体 tumor protein D52 like 1 (TPD52L1) 抗体 tumor protein D52-like 1 (tpd52l1) 抗体 tumor protein D52-like 1 (TPD52L1) 抗体 d53 抗体 D53 抗体 hD53 抗体 MGC84190 抗体 TPD52L1 抗体 zgc:110003 抗体