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Topoisomerase II alpha 抗体

(Topoisomerase (DNA) II alpha 170kDa (TOP2A))
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. [provided by RefSeq, Jul 2010].
Topoisomerase II alpha 抗体 Topoisomerase II alpha 抗体 Topoisomerase II alpha 抗体 (ABIN7075937)

TOP2A 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

Topoisomerase II alpha 抗体  (AA 1352-1493) Topoisomerase II alpha 抗体  (AA 1352-1493) Topoisomerase II alpha 抗体 (AA 1352-1493) (ABIN6940773)

TOP2A 适用: 人, 小鼠 WB, IHC, IF, StM 宿主: 小鼠 Monoclonal TOP2A-1361 unconjugated

Topoisomerase II alpha 抗体  (AA 1435-1531) Topoisomerase II alpha 抗体  (AA 1435-1531) Topoisomerase II alpha 抗体 (AA 1435-1531) (ABIN563224)

TOP2A 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E2 unconjugated

Topoisomerase II alpha 抗体 by 适用

Find Topoisomerase II alpha 抗体 for a variety of species such as anti-Human Topoisomerase II alpha, anti-Mouse Topoisomerase II alpha, anti-Rat Topoisomerase II alpha. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find Topoisomerase II alpha 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Topoisomerase II alpha 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse, Rat
Application IHC, IF
Validations
  • (12)
Cat. No. ABIN7075937
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, IF, StM
Validations
  • (7)
Cat. No. ABIN6940773
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (1)
  • (5)
Cat. No. ABIN563224
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, FACS, ICC
Validations
  • (7)
Cat. No. ABIN7193564
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (5)
Cat. No. ABIN7193523
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, ELISA, IF, ICC
Validations
  • (4)
Cat. No. ABIN6265673
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (3)
Cat. No. ABIN7184512
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN2854837
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (4)
Cat. No. ABIN653195
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN7180100
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7127851
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7138410
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN5589934
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), FACS
Validations
  • (2)
Cat. No. ABIN5589937
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (3)
Cat. No. ABIN1533609
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Topoisomerase II alpha 抗体

Jiang, Mohan, Endo, Shen, Wu: "Type IIB DNA topoisomerase is downregulated by trastuzumab and doxorubicin to synergize cardiotoxicity." in: Oncotarget, Vol. 9, Issue 5, pp. 6095-6108, (2018) (PubMed).

Poonperm, Takata, Hamano, Matsuda, Uchiyama, Hiraoka, Fukui: "Chromosome Scaffold is a Double-Stranded Assembly of Scaffold Proteins." in: Scientific reports, Vol. 5, pp. 11916, (2015) (PubMed).

Lindén, Segersten, Runeson, Wester, Busch, Pettersson, Lind, Malmström: "Tumour expression of bladder cancer-associated urinary proteins." in: BJU international, Vol. 112, Issue 3, pp. 407-15, (2013) (PubMed).

Andersson, Konrad, Ashok, Pontén, Hober, Asplund: "Antibodies biotinylated using a synthetic Z-domain from protein A provide stringent in situ protein detection." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 61, Issue 11, pp. 773-84, (2013) (PubMed).

Mondal, Parvin: "DNA topoisomerase IIalpha is required for RNA polymerase II transcription on chromatin templates." in: Nature, Vol. 413, Issue 6854, pp. 435-8, (2001) (PubMed).

Aliases for Topoisomerase II alpha 抗体

DNA topoisomerase II alpha (TOP2A) 抗体
DNA topoisomerase II, alpha isozyme (Bm1_08705) 抗体
topoisomerase (DNA) II alpha (Top2a) 抗体
DNA topoisomerase II alpha (Top2a) 抗体
topoisomerase (DNA) II alpha (TOP2A) 抗体
Zincin-like metalloproteases family protein (AT5G10540) 抗体
DNA topoisomerase II alpha (top2a) 抗体
F12B17.110 抗体
F12B17_110 抗体
fc08c07 抗体
thimet metalloendopeptidase 2 抗体
Top-2 抗体
TOP-2 抗体
TOP2 抗体
TOP2A 抗体
TP2A 抗体
wu:fc08c07 抗体
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