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Topoisomerase II alpha 抗体

(Topoisomerase (DNA) II alpha 170kDa (TOP2A))

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. [provided by RefSeq, Jul 2010].

recommended

Topoisomerase II alpha 抗体 (ABIN7075937)

TOP2A 适用: 小鼠, 大鼠 IF, IHC 宿主: 兔 Polyclonal unconjugated

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recommended

Topoisomerase II alpha 抗体 (AA 1100-1530) (ABIN7193564)

TOP2A 适用: 人, 大鼠 ELISA, FACS, ICC, WB 宿主: 小鼠 Monoclonal 6C12G12 unconjugated

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recommended

Topoisomerase II alpha 抗体 (AA 1352-1493) (ABIN6940773)

TOP2A 适用: 人, 小鼠 IF, IHC, StM, WB 宿主: 小鼠 Monoclonal TOP2A-1361 unconjugated

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Topoisomerase II alpha 抗体 by 适用

Find Topoisomerase II alpha 抗体 for a variety of species such as anti-Human Topoisomerase II alpha, anti-Mouse Topoisomerase II alpha, anti-Rat Topoisomerase II alpha. The species listed below are among those available. Click on a link to go to the corresponding products.

Topoisomerase II alpha 抗体 by 应用范围

Find Topoisomerase II alpha 抗体 validated for a specific application such as WB, IHC, ELISA, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Topoisomerase II alpha 抗体 by 抗体来源

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Topoisomerase II alpha 抗体 by 抗原表位

Find Topoisomerase II alpha 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Topoisomerase II alpha 抗体 by 克隆形成能力

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Topoisomerase II alpha 抗体 by 克隆

Find Topoisomerase II alpha 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

Topoisomerase II alpha 抗体 by 标记

Find Topoisomerase II alpha 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Topoisomerase II alpha 抗体

Product

Reactivity

Application

Validations

Cat. No.

Quantity

Datasheet

anti-Topoisomerase II alpha 抗体

Reactivity Mouse, Rat

Application IF, IHC

Validations

(12)

Cat. No. ABIN7075937

Quantity 100 μL

Datasheet Datasheet

anti-Topoisomerase II alpha 抗体 (AA 1100-1530)

Reactivity Human, Rat

Application ELISA, FACS, ICC, WB

Validations

Cat. No. ABIN7193564

Quantity 0.1 mg

Datasheet Datasheet

anti-Topoisomerase II alpha 抗体 (AA 1352-1493)

Reactivity Human, Mouse

Application IF, IHC, StM, WB

Validations

Cat. No. ABIN6940773

Quantity 100 μg

Datasheet Datasheet

anti-Topoisomerase II alpha 抗体 (AA 1435-1531)

Reactivity Human

Application IF, IHC (p), ELISA, WB

Validations

Cat. No. ABIN563224

Quantity 100 μg

Datasheet Datasheet

anti-Topoisomerase II alpha 抗体 (AA 1100-1530)

Reactivity Human

Application ELISA, IHC, WB

Validations

Cat. No. ABIN7193523

Quantity 0.1 mg

Datasheet Datasheet

anti-Topoisomerase II alpha 抗体 (Internal Region)

Reactivity Human, Mouse

Application ELISA, ICC, IF, IHC, WB

Validations

Cat. No. ABIN6265673

Quantity 100 μL

Datasheet Datasheet

anti-Topoisomerase II alpha 抗体 (C-Term)

Reactivity Human

Application IF, IHC (p), WB

Validations

Cat. No. ABIN653195

Quantity 400 μL

Datasheet Datasheet

anti-Topoisomerase II alpha 抗体 (N-Term)

Reactivity Human

Application ELISA, IF, IHC, WB

Validations

Cat. No. ABIN7184512

Quantity 100 μL

Datasheet Datasheet

anti-Topoisomerase II alpha 抗体 (C-Term)

Reactivity Human

Application IHC (p), WB

Validations

Cat. No. ABIN2854837

Quantity 100 μL

Datasheet Datasheet

anti-Topoisomerase II alpha 抗体 (N-Term)

Reactivity Human

Application IC, IF, IP, IHC, WB

Validations

Cat. No. ABIN7297180

Quantity 100 μL

Datasheet Datasheet

anti-Topoisomerase II alpha 抗体 (AA 1-50)

Reactivity Human

Application IF, IHC, ELISA, WB

Validations

Cat. No. ABIN1533609

Quantity 100 μg

Datasheet Datasheet

anti-Topoisomerase II alpha 抗体

Reactivity Human

Application IHC (p), IP, WB

Validations

Cat. No. ABIN1109281

Quantity 0.1 mL

Datasheet Datasheet

anti-Topoisomerase II alpha 抗体 (Thr1343)

Reactivity Human

Application ELISA, WB

Validations

Cat. No. ABIN7180100

Quantity 100 μL

Datasheet Datasheet

anti-Topoisomerase II alpha 抗体

Reactivity Human

Application ELISA, IHC, WB

Validations

Cat. No. ABIN7127851

Quantity 100 μL

Datasheet Datasheet

anti-Topoisomerase II alpha 抗体 (pSer1469)

Reactivity Human, Mouse

Application IHC, WB

Validations

Cat. No. ABIN6254985

Quantity 100 μL

Datasheet Datasheet

Latest Publications for our Topoisomerase II alpha 抗体

Jiang, Mohan, Endo, Shen, Wu: "Type IIB DNA topoisomerase is downregulated by trastuzumab and doxorubicin to synergize cardiotoxicity." in: Oncotarget, Vol. 9, Issue 5, pp. 6095-6108, (2018) (PubMed).

Poonperm, Takata, Hamano, Matsuda, Uchiyama, Hiraoka, Fukui: "Chromosome Scaffold is a Double-Stranded Assembly of Scaffold Proteins." in: Scientific reports, Vol. 5, pp. 11916, (2015) (PubMed).

Lindén, Segersten, Runeson, Wester, Busch, Pettersson, Lind, Malmström: "Tumour expression of bladder cancer-associated urinary proteins." in: BJU international, Vol. 112, Issue 3, pp. 407-15, (2013) (PubMed).

Andersson, Konrad, Ashok, Pontén, Hober, Asplund: "Antibodies biotinylated using a synthetic Z-domain from protein A provide stringent in situ protein detection." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 61, Issue 11, pp. 773-84, (2013) (PubMed).

Mondal, Parvin: "DNA topoisomerase IIalpha is required for RNA polymerase II transcription on chromatin templates." in: Nature, Vol. 413, Issue 6854, pp. 435-8, (2001) (PubMed).

Aliases for Topoisomerase II alpha 抗体

DNA topoisomerase II alpha (TOP2A) 抗体
DNA topoisomerase II, alpha isozyme (Bm1_08705) 抗体
topoisomerase (DNA) II alpha (Top2a) 抗体
DNA topoisomerase II alpha (Top2a) 抗体
topoisomerase (DNA) II alpha (TOP2A) 抗体
Zincin-like metalloproteases family protein (AT5G10540) 抗体
DNA topoisomerase II alpha (top2a) 抗体
F12B17.110 抗体
F12B17_110 抗体
fc08c07 抗体
thimet metalloendopeptidase 2 抗体
Top-2 抗体
TOP-2 抗体
TOP2 抗体
TOP2A 抗体
TP2A 抗体
wu:fc08c07 抗体

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Popular Topoisomerase II alpha 抗体

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Aliases for Topoisomerase II alpha 抗体

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