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Topoisomerase II alpha 抗体 (AA 1352-1493)

TOP2A 适用: 人, 小鼠 WB, IHC, IF, StM 宿主: 小鼠 Monoclonal TOP2A-1361 unconjugated
产品编号 ABIN6940773
发货至: 中国
  • 抗原 See all Topoisomerase II alpha (TOP2A) 抗体
    Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
    抗原表位
    • 19
    • 17
    • 11
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    • 7
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    AA 1352-1493
    适用
    • 146
    • 60
    • 30
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    人, 小鼠
    宿主
    • 110
    • 37
    小鼠
    克隆类型
    • 97
    • 50
    单克隆
    标记
    • 72
    • 11
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Topoisomerase II alpha antibody is un-conjugated
    应用范围
    • 98
    • 55
    • 52
    • 47
    • 26
    • 19
    • 13
    • 6
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)
    特异性
    It recognizes a 170 kDa protein, which is identified as topoisomerase II is also implicated in drug resistance of tumor cells and has been shown to be over-expressed in many human cancers. Decreased expression of Topo IIa is the predominant mechanism of resistance to several chemotherapeutic agents.
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant human Topoisomerase II alpha fragment (aa1352-1493)
    克隆位点
    TOP2A-1361
    亚型
    IgG2b kappa
    Top Product
    Discover our top product TOP2A Primary Antibody
  • 应用备注

    Positive Control: HeLa cells. Tonsil.

    Known Application: Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
    别名
    TOP2A (TOP2A 产品)
    别名
    TOP2 antibody, TP2A antibody, TOP2A antibody, Top-2 antibody, TOP-2 antibody, F12B17.110 antibody, F12B17_110 antibody, thimet metalloendopeptidase 2 antibody, fc08c07 antibody, wu:fc08c07 antibody, DNA topoisomerase II alpha antibody, DNA topoisomerase II, alpha isozyme antibody, topoisomerase (DNA) II alpha antibody, Zincin-like metalloproteases family protein antibody, TOP2A antibody, Bm1_08705 antibody, Top2a antibody, AT5G10540 antibody, top2a antibody
    分子量
    170kDa
    基因ID
    7153
    UniProt
    P11388
    途径
    Cell Division Cycle, Mitotic G1-G1/S Phases
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