Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent translational repression and siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins (By similarity).
Murakami, Tamori, Itami, Tanahashi, Toyoda, Tanaka, Wu, Brojigin, Kaneoka, Maeda, Kumada, Kawada, Kubo, Kuroda: "The expression level of miR-18b in hepatocellular carcinoma is associated with the grade of malignancy and prognosis." in: BMC cancer, Vol. 13, pp. 99, (2013) (PubMed).
Schneider, Najand, Chaker, Pare, Haskins, Hughes, Hobman, Locke, Simmonds: "Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development." in: The Journal of cell biology, Vol. 174, Issue 3, pp. 349-58, (2006) (PubMed).