TNRC6B 抗体 (AA 25-70)
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- 抗原 See all TNRC6B 抗体
- TNRC6B (Trinucleotide Repeat Containing 6B (TNRC6B))
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抗原表位
- AA 25-70
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNRC6B antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human TNRC6B
- 亚型
- IgG
- Top Product
- Discover our top product TNRC6B Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- TNRC6B (Trinucleotide Repeat Containing 6B (TNRC6B))
- 别名
- TNRC6B (TNRC6B 产品)
- 别名
- hm:zeh0114 antibody, im:6968518 antibody, wu:fa01f05 antibody, 2700090M07Rik antibody, A730065C02Rik antibody, AI848765 antibody, D230019K20Rik antibody, Cbl27 antibody, trinucleotide repeat containing 6b antibody, trinucleotide repeat containing 6B antibody, trinucleotide repeat containing 6B S homeolog antibody, tnrc6b antibody, TNRC6B antibody, tnrc6b.S antibody, Tnrc6b antibody
- 背景
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Synonyms: KIAA1093, TNRC 6B, Trinucleotide repeat containing 6B, Trinucleotide repeat containing gene 6B protein, TNR6B_HUMAN.
Background: TNRC6B is a 1,723 amino acid protein that exists as two alternatively spliced isoforms and is thought to be involved in mRNA cleavage events. Expressed ubiquitously, TNRC6B contains one glycine/tryptophan (GW)-rich N-terminal domain, one central glutamine-rich region and one C-terminal RNA recognition motif and is encoded by a gene that maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.
- 途径
- Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway
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