TNKS2 蛋白
(Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2))
Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates poly-ADP-ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates poly-ADP-ribosylation of TERF1, thereby contributing to the regulation of telomere length. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles (By similarity).$.
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6 results
TNKS2
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
SDS, WB, Imm, PC
custom-made
TNKS2
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
custom-made
TNKS2
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
Aliases for TNKS2 蛋白
tankyrase 2 (TNKS2) 蛋白tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 (Tnks2) 蛋白
tankyrase 2 (Tnks2) 蛋白
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 (TNKS2) 蛋白
tankyrase 2 (tnks2) 蛋白
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase S homeolog (tnks.S) 蛋白
5430432P15Rik 蛋白
AA517131 蛋白
AI662480 蛋白
ARTD6 蛋白
PARP-5b 蛋白
PARP-5c 蛋白
PARP5B 蛋白
PARP5C 蛋白
pART6 蛋白
TANK2 蛋白
Tank2 蛋白
tankyrase-1 蛋白
tankyrase-2 蛋白
TNKL 蛋白
tnks 蛋白
TNKS-2 蛋白
tnks.L 蛋白
TNKS2 蛋白
tnks2 蛋白
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