TNFSF13 蛋白
(Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified\; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010].
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35 results
TNFSF13
宿主: 人
宿主: 小麦胚
Recombinant
WB, ELISA, AP, AA
1 image
1 reference
TNFSF13
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
1 image
TNFSF13
宿主: 人
宿主: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
1 image
TNFSF13
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 85 % by SDS - PAGE
SDS
1 image
TNFSF13
宿主: 人, 小鼠
宿主: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
SDS
Active
1 reference
TNFSF13
宿主: 人, 小鼠
宿主: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
SDS
Active
9 references
TNFSF13
宿主: 人
宿主: 人细胞
Recombinant
> 95 % as determined by reducing SDS-PAGE.
TNFSF13
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
> 90 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
TNFSF13
宿主: 小鼠
宿主: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
SDS, WB, Imm, ELISA, AcA
Active
TNFSF13
宿主: 人
宿主: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
SDS, WB, Imm, ELISA, AcA
Active
TNFSF13
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Latest Publications for our TNFSF13 蛋白
: "STAT-3 activation by differential cytokines is critical for human in vivo-generated plasma cell survival and Ig secretion." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 10, pp. 4996-5004, (2013) (PubMed).: "Selective APRIL blockade delays systemic lupus erythematosus in mouse." in: PLoS ONE, Vol. 7, Issue 2, pp. e31837, (2012) (PubMed).
: "Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 9, pp. 3701-6, (2011) (PubMed).
: "TACI regulates IgA production by APRIL in collaboration with HSPG." in: Blood, Vol. 109, Issue 7, pp. 2961-7, (2007) (PubMed).
: "BAFF and APRIL support chronic lymphocytic leukemia B-cell survival through activation of the canonical NF-kappaB pathway." in: Blood, Vol. 109, Issue 2, pp. 703-10, (2007) (PubMed).
: "APRIL and BAFF promote increased viability of replicating human B2 cells via mechanism involving cyclooxygenase 2." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 11, pp. 6736-51, (2006) (PubMed).
: "BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway." in: The Journal of experimental medicine, Vol. 202, Issue 10, pp. 1363-74, (2005) (PubMed).
: "Potential role of APRIL as autocrine growth factor for megakaryocytopoiesis." in: Blood, Vol. 104, Issue 10, pp. 3169-72, (2004) (PubMed).
: "Lymphoma B cells evade apoptosis through the TNF family members BAFF/BLyS and APRIL." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 5, pp. 3268-79, (2004) (PubMed).
: "DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL." in: Nature immunology, Vol. 3, Issue 9, pp. 822-9, (2002) (PubMed).
Aliases for TNFSF13 蛋白
TNF superfamily member 13 (TNFSF13) 蛋白tumor necrosis factor (ligand) superfamily, member 13 (Tnfsf13) 蛋白
acidic leucine-rich nuclear phosphoprotein 32 family member B (LOC494442) 蛋白
tumor necrosis factor (ligand) superfamily, member 13 (tnfsf13) 蛋白
TNF superfamily member 13 (Tnfsf13) 蛋白
tumor necrosis factor (ligand) superfamily, member 13 (TNFSF13) 蛋白
2310026N09Rik 蛋白
ANP32B 蛋白
APRIL 蛋白
April 蛋白
april 蛋白
CD256 蛋白
SLAN 蛋白
TALL-2 蛋白
TALL2 蛋白
Tall2 蛋白
tnf13 蛋白
TNLG7B 蛋白
TRDL-1 蛋白
Trdl1 蛋白
ZTNF2 蛋白
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