TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 抗体
(TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))
The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
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Latest Publications for our TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 抗体
: "XIAP induces NF-kappaB activation via the BIR1/TAB1 interaction and BIR1 dimerization." in: Molecular cell, Vol. 26, Issue 5, pp. 689-702, (2007) (PubMed).Aliases for TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 抗体
TGF-beta activated kinase 1 and MAP3K7 binding protein 3 (TAB3) 抗体TGF-beta activated kinase 1/MAP3K7 binding protein 3 (Tab3) 抗体
TGF-beta activated kinase 1/MAP3K7 binding protein 3 S homeolog (tab3.S) 抗体
TGF-beta activated kinase 1/MAP3K7 binding protein 3 (tab3) 抗体
TGF-beta activated kinase 1 and MAP3K7 binding protein 3 (Tab3) 抗体
4921526G09Rik 抗体
MAP3K7IP3 抗体
Map3k7ip3 抗体
map3k7ip3 抗体
map3k7ip3l 抗体
mKIAA4135 抗体
NAP1 抗体
nap1 抗体
si:ch211-232d19.8 抗体
si:dkey-30h22.6 抗体
tab3 抗体
tab3-a 抗体
tab3-b 抗体
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