TFF1 蛋白
(Trefoil Factor 1 (TFF1))
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008].
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Latest Publications for our TFF1 蛋白
: "Proteolytic effects of gingipains on trefoil factor family peptides." in: Clinical oral investigations, Vol. 22, Issue 2, pp. 1009-1018, (2018) (PubMed).: "High trefoil factor 1 (TFF1) expression in human retinoblastoma cells correlates with low growth kinetics, increased cyclin-dependent kinase (CDK) inhibitor levels and a selective down-regulation of ..." in: Histochemistry and cell biology, Vol. 139, Issue 2, pp. 323-38, (2014) (PubMed).
: "Pathophysiological investigation of the gastric surface mucous gel layer of patients with Helicobacter pylori infection by using immunoassays for trefoil factor family 2 and gastric gland mucous ..." in: Digestive diseases and sciences, Vol. 56, Issue 12, pp. 3498-506, (2011) (PubMed).
: "The aurora kinase A regulates GSK-3beta in gastric cancer cells." in: Oncogene, Vol. 28, Issue 6, pp. 866-75, (2009) (PubMed).
Aliases for TFF1 蛋白
trefoil factor 1 (TFF1) 蛋白trefoil factor 1 (Tff1) 蛋白
trefoil factor 1 S homeolog (tff1.S) 蛋白
trefoil factor 1, gene 2 S homeolog (tff1.2.S) 蛋白
trefoil factor 1 (LOC100358238) 蛋白
BCEI 蛋白
Bcei 蛋白
bcei 蛋白
D21S21 蛋白
d21s21 蛋白
HP1.A 蛋白
hp1.a 蛋白
HPS2 蛋白
hps2 蛋白
p1 蛋白
p1-a 蛋白
pNR-2 蛋白
pnr-2 蛋白
pS2 蛋白
PS2 蛋白
ps2 蛋白
Ps2 蛋白
tff1 蛋白
TFF1 蛋白
xP1 蛋白
xp1 蛋白
xp1-L 蛋白
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