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TdT 蛋白

(Deoxynucleotidyltransferase, terminal (DNTT))
This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008].

Popular TdT 蛋白

Aliases for TdT 蛋白

DNA nucleotidylexotransferase (DNTT) 蛋白
deoxynucleotidyltransferase, terminal (dntt) 蛋白
deoxynucleotidyltransferase, terminal (Dntt) 蛋白
DNA nucleotidylexotransferase L homeolog (dntt.L) 蛋白
DNA nucleotidylexotransferase (Dntt) 蛋白
terminal deoxynucleotidyl transferase (tdt) 蛋白
BB160593 蛋白
dntt 蛋白
dntt-A 蛋白
TdT 蛋白
TDT 蛋白
Tdt 蛋白
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