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TDP1 蛋白

(Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform. [provided by RefSeq, Jul 2008].

14 results :

custom-made TDP1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7564369
 
custom-made TDP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7555891
 
TDP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Pubmed 1 reference
产品编号 ABIN1322434
 
TDP1 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
产品编号 ABIN7281254
 
TDP1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant SDS
产品编号 ABIN2132102
 
TDP1 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS, WB, Imm, PC
产品编号 ABIN7419694
 
TDP1 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant >90 % SDS, WB, Imm, PC
产品编号 ABIN7420363
 
TDP1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS, WB, Imm, PC
产品编号 ABIN7423144
 
custom-made TDP1 宿主: 小鼠 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA
产品编号 ABIN3136184
 
custom-made TDP1 宿主: 人 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA
产品编号 ABIN3096148
 
TDP1 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant SDS, WB, ELISA, IP
产品编号 ABIN6119431
 
TDP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2733393
 
TDP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2733392
 
TDP1 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN7586304
 
  • 类型 Protein
    • Protein
  • 应用范围
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Antibody Production (AbP)
    • Standard (STD)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Immunoprecipitation (IP)
  • 适用
    • Human
    • Mouse
    • Rat
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Baculovirus infected Insect Cells
    • Wheat germ
    • Yeast
  • 抗原表位
    • AA 1-608
    • AA 1-609
    • AA 1-151
    • AA 1-271
    • AA 4-215
    • Transcript Variant 1
    • Transcript Variant 2
  • 标记
    • His tag
    • His tag,GST tag
    • Myc-DYKDDDDK Tag
    • Strep Tag
    • 非结合性
    • GST tag
  • 蛋白类型
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • OriGene
    • Abbexa
    • CUSABIO

Latest Publications for our TDP1 蛋白

Takahashi, Tada, Igarashi, Koyama, Date, Yokoseki, Shiga, Yoshida, Tsuji, Nishizawa, Onodera: "Aprataxin, causative gene product for EAOH/AOA1, repairs DNA single-strand breaks with damaged 3'-phosphate and 3'-phosphoglycolate ends." in: Nucleic acids research, Vol. 35, Issue 11, pp. 3797-809, (2007) (PubMed).

Aliases for TDP1 蛋白

tyrosyl-DNA phosphodiesterase 1 (TDP1) 蛋白
tyrosyl-DNA Phosphodiesterase (Tdp1) (Tc00.1047053511191.10) 蛋白
tyrosyl-DNA phosphodiesterase 1 (Tdp1) 蛋白
tyrosyl-DNA phosphodiesterase 1 L homeolog (tdp1.L) 蛋白
tyrosyl-DNA phosphodiesterase 1 (tdp1) 蛋白
tyrosyl-DNA phosphodiesterase-like protein (TDP1) 蛋白
tyrosyl-DNA phosphodiesterase 1 (PTRG_11198) 蛋白
tyrosyl-DNA phosphodiesterase 1 (MCYG_02121) 蛋白
tyrosyl-DNA phosphodiesterase 1 (MGYG_03035) 蛋白
2810481F14Rik 蛋白
4921509N21Rik 蛋白
AI838772 蛋白
AW493413 蛋白
E430034L06Rik 蛋白
F8M21.60 蛋白
F8M21_60 蛋白
MGC83708 蛋白
MLZ-501 蛋白
SCAN1 蛋白
tdp1 蛋白
TDP1 蛋白
tyrosyl-DNA phosphodiesterase 1 蛋白
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