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TCEB1 抗体

(Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))
This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. [provided by RefSeq, Mar 2011].

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  • 抗原: TCEB1
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN8125266
TCEB1 抗体 (AA 40-120) TCEB1 · Primary Antibody 人, 小鼠, 大鼠 兔 Polyclonal
  • ELISA (ELISA: 所列应用)
  • WB (Western Blotting: 所列应用)
  • 50 μL
发货至: 中国
Primary Antibody
  • ELISA (ELISA: 所列应用)
  • WB (Western Blotting: 所列应用)
适用
人, 小鼠, 大鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
AA 40-120
产品编号 ABIN8125266

Latest Publications for our TCEB1 抗体

Lee, Frattini, Bansal, Castano, Sherman, Hutchinson, Bruce, Califano, Liu, Cardozo, Iavarone, Lasorella: "An ID2-dependent mechanism for VHL inactivation in cancer." in: Nature, Vol. 529, Issue 7585, pp. 172-7, (2016) (PubMed).

Hubbi, Luo, Baek, Semenza: "MCM proteins are negative regulators of hypoxia-inducible factor 1." in: Molecular cell, Vol. 42, Issue 5, pp. 700-12, (2011) (PubMed).

Mao, Gluck, Chen, Starokadomskyy, Li, Maine, Burstein: "COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding." in: The Journal of biological chemistry, Vol. 286, Issue 37, pp. 32355-65, (2011) (PubMed).

Mao, Gluck, Li, Maine, Li, Zaidi, Repaka, Mayo, Burstein: "GCN5 is a required cofactor for a ubiquitin ligase that targets NF-kappaB/RelA." in: Genes & development, Vol. 23, Issue 7, pp. 849-61, (2009) (PubMed).

Maine, Mao, Komarck, Burstein: "COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase." in: The EMBO journal, Vol. 26, Issue 2, pp. 436-47, (2007) (PubMed).

Bradsher, Jackson, Conaway, Conaway: "RNA polymerase II transcription factor SIII. I. Identification, purification, and properties." in: The Journal of biological chemistry, Vol. 268, Issue 34, pp. 25587-93, (1994) (PubMed).

Aliases for TCEB1 抗体

elongin C (Eloc) 抗体
elongin C L homeolog (eloc.L) 抗体
elongin C (ELOC) 抗体
transcription elongation factor B (SIII), polypeptide 1b (tceb1b) 抗体
2610043E24Rik 抗体
2610301I15Rik 抗体
AA407206 抗体
AI987979 抗体
AW049146 抗体
eloC 抗体
fb09f09 抗体
SIII 抗体
TCEB1 抗体
wu:fb09f09 抗体
zgc:92635 抗体
zgc:111990 抗体
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