TCEB1 产品
(Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))
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This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. [provided by RefSeq, Mar 2011].
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Featured TCEB1 Categories
Recommended TCEB1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
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Application
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- (3)
Cat. No.
ABIN6148930
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, ICC, IP
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- (2)
Cat. No.
ABIN7445219
Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN7128027
Quantity
100 μL
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Datasheet
Recommended TCEB1 ELISA试剂盒
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Reactivity
Analytical Method
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Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6228298
Quantity
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Datasheet
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Recommended TCEB1 蛋白
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Reactivity
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Source
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Cat. No.
ABIN1322346
Quantity
10 μg
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Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
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- (1)
Cat. No.
ABIN3121085
Quantity
1 mg
Datasheet
Datasheet
Reactivity
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Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419931
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TCEB1 Products
: "An ID2-dependent mechanism for VHL inactivation in cancer." in: Nature, Vol. 529, Issue 7585, pp. 172-7, (2016) (PubMed).: "MCM proteins are negative regulators of hypoxia-inducible factor 1." in: Molecular cell, Vol. 42, Issue 5, pp. 700-12, (2011) (PubMed).
: "COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding." in: The Journal of biological chemistry, Vol. 286, Issue 37, pp. 32355-65, (2011) (PubMed).
: "GCN5 is a required cofactor for a ubiquitin ligase that targets NF-kappaB/RelA." in: Genes & development, Vol. 23, Issue 7, pp. 849-61, (2009) (PubMed).
: "COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase." in: The EMBO journal, Vol. 26, Issue 2, pp. 436-47, (2007) (PubMed).
: "RNA polymerase II transcription factor SIII. I. Identification, purification, and properties." in: The Journal of biological chemistry, Vol. 268, Issue 34, pp. 25587-93, (1994) (PubMed).
Synonyms and alternative names related to TCEB1
elongin C (Eloc), elongin C L homeolog (eloc.L), elongin C (ELOC), transcription elongation factor B (SIII), polypeptide 1b (tceb1b), 2610043E24Rik, 2610301I15Rik, AA407206, AI987979, AW049146, eloC, fb09f09, SIII, TCEB1, wu:fb09f09, zgc:92635, zgc:111990Protein level used designations for TCEB1
- RNA polymerase II transcription factor SIII subunit C
- SIII p15
- eloC
- elongin 15 kDa subunit
- elongin C
- elongin-C
- stromal membrane-associated protein SMAP1B homolog
- transcription elongation factor B polypeptide 1
- elongation factor SIII p15 subunit
- Elongin C
- transcription elongation factor B (SIII), polypeptide 1
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