TCF4 产品
(Transcription Factor 4 (TCF4))
Categories
This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. Multiple alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq, Aug 2011].
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Featured TCF4 Categories
TCF4 抗体
High quality antibodies with extensive validation data.
TCF4 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
TCF4 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TCF4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (3)
- (5)
Cat. No.
ABIN520754
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (6)
Cat. No.
ABIN3021530
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC
Validations
- (4)
Cat. No.
ABIN5542392
Quantity
0.1 mg
Datasheet
Datasheet
Recommended TCF4 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970768
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1162244
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1162245
Quantity
96 tests
Datasheet
Datasheet
Recommended TCF4 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1322369
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125438
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125439
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our TCF4 Products
: "Forkhead box (FOX) G1 promotes hepatocellular carcinoma epithelial-Mesenchymal transition by activating Wnt signal through forming T-cell factor-4/Beta-catenin/FOXG1 complex." in: Journal of experimental & clinical cancer research : CR, Vol. 38, Issue 1, pp. 475, (2020) (PubMed).: "Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle." in: Cell reports, Vol. 27, Issue 7, pp. 2029-2035.e5, (2019) (PubMed).
: "A PGC1α-mediated transcriptional axis suppresses melanoma metastasis." in: Nature, Vol. 537, Issue 7620, pp. 422-426, (2016) (PubMed).
: "Knockdown of human TCF4 affects multiple signaling pathways involved in cell survival, epithelial to mesenchymal transition and neuronal differentiation." in: PLoS ONE, Vol. 8, Issue 8, pp. e73169, (2013) (PubMed).
: "Sox4 functions as a positive regulator of β-catenin signaling through upregulation of TCF4 during morular differentiation of endometrial carcinomas." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 92, Issue 4, pp. 511-21, (2012) (PubMed).
: "Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching." in: Pigment cell & melanoma research, Vol. 24, Issue 4, pp. 631-42, (2011) (PubMed).
: "Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis." in: Blood, Vol. 115, Issue 20, pp. 4138-47, (2010) (PubMed).
: "Beta-catenin signaling mediates CD4 expression on mature CD8+ T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 4, pp. 2013-9, (2010) (PubMed).
: "p53 mediates senescence-like arrest induced by chronic replicational stress." in: Molecular and cellular biology, Vol. 27, Issue 15, pp. 5336-51, (2007) (PubMed).
: "Transcription factor MITF regulates cardiac growth and hypertrophy." in: The Journal of clinical investigation, Vol. 116, Issue 10, pp. 2673-81, (2007) (PubMed).
Synonyms and alternative names related to TCF4
transcription factor 4 (TCF4), transcription factor 4 (Tcf4), transcription factor 4 (tcf4), transcription factor 4 S homeolog (tcf4.S), 5730422P05Rik, ASP-I2, bHLHb19, E2-2, e2-A, E2.2, ITF-2, ITF-2b, ITF2, ME2, MITF-2A, MITF-2B, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, TCF-4, Tcf-4, tcf-4, TCF7L2, TFE, XE2, Xtcf-4, Xtcf4Protein level used designations for TCF4
- SL3-3 enhancer factor 2
- class B basic helix-loop-helix protein 19
- immunoglobulin transcription factor 2
- MITF-2
- Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2)
- class A helix-loop-helix transcription factor ME2
- immunoglobulin transcription factor-2
- ITF-2
- R8f DNA-binding protein
- RITF-2
- SEF-2
- TCF-4
- thyroglobulin promoter transcription factor TFE
- transcription factor 7-like 2 (T-cell specific, HMG-box)
- transcriptional factor 4
- tcf4l
- helix-loop-helix transcription factor
- LOW QUALITY PROTEIN: transcription factor 4
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