Sjogren Syndrome Antigen B 抗体
(Sjogren Syndrome Antigen B (SSB))
The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. [provided by RefSeq, Nov 2011].
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Latest Publications for our Sjogren Syndrome Antigen B 抗体
: "Toll-like receptor 3 stimulation promotes Ro52/TRIM21 synthesis and nuclear redistribution in salivary gland epithelial cells, partially via type I interferon pathway." in: Clinical and experimental immunology, Vol. 178, Issue 3, pp. 548-60, (2014) (PubMed).: "RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP." in: Nucleic acids research, Vol. 41, Issue 8, pp. 4686-98, (2013) (PubMed).
: "Phosphorylation of human La protein at Ser 366 by casein kinase II contributes to hepatitis B virus replication and expression in vitro." in: Journal of viral hepatitis, Vol. 20, Issue 1, pp. 24-33, (2012) (PubMed).
: "Regulation of hepatitis C virus translation initiation by iron: role of eIF3 and La protein." in: Virus research, Vol. 167, Issue 2, pp. 302-9, (2012) (PubMed).
: "The cellular protein La functions in enhancement of virus release through lipid rafts facilitated by murine leukemia virus glycosylated Gag." in: mBio, Vol. 2, Issue 1, pp. e00341-10, (2011) (PubMed).
: "Akt phosphorylation of La regulates specific mRNA translation in glial progenitors." in: Oncogene, Vol. 28, Issue 1, pp. 128-39, (2009) (PubMed).
: "Cellular La protein shields nonsegmented negative-strand RNA viral leader RNA from RIG-I and enhances virus growth by diverse mechanisms." in: Journal of virology, Vol. 82, Issue 16, pp. 7977-87, (2008) (PubMed).
: "Structural analysis reveals conformational plasticity in the recognition of RNA 3' ends by the human La protein." in: Structure (London, England : 1993), Vol. 16, Issue 6, pp. 852-62, (2008) (PubMed).
: "Structural basis for recognition and sequestration of UUU(OH) 3' temini of nascent RNA polymerase III transcripts by La, a rheumatic disease autoantigen." in: Molecular cell, Vol. 21, Issue 1, pp. 75-85, (2006) (PubMed).
: "A carboxy-terminal basic region controls RNA polymerase III transcription factor activity of human La protein." in: Molecular and cellular biology, Vol. 17, Issue 10, pp. 5823-32, (1997) (PubMed).
Aliases for Sjogren Syndrome Antigen B 抗体
Sjogren syndrome antigen B (SSB) 抗体Sjogren syndrome antigen B L homeolog (ssb.L) 抗体
single stranded DNA binding protein 1 (SSBP1) 抗体
Sjogren syndrome antigen B (Ssb) 抗体
Sjogren syndrome antigen B S homeolog (ssb.S) 抗体
Sjogren syndrome antigen B (autoantigen La) (ssb) 抗体
La 抗体
laa-a 抗体
lab1 抗体
LARP3 抗体
larp3 抗体
Mt-SSB 抗体
MtSSB 抗体
SS-B 抗体
ssb 抗体
ssb-a 抗体
ssb-b 抗体
Ssbp1 抗体
wu:fb17f11 抗体
zgc:55588 抗体
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