This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome)\; translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. [provided by RefSeq, Jul 2008].
Peng, Ivanov, Oh, Lau, Rauscher: "Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery." in: The Journal of biological chemistry, Vol. 284, Issue 51, pp. 35670-80, (2009) (PubMed).
Wu, Chen, Li, Lau, Shih: "Regulation of monoamine oxidase A by the SRY gene on the Y chromosome." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 11, pp. 4029-38, (2009) (PubMed).
Aliases for SRY 抗体
sex determining region Y (SRY) 抗体 sex determining region Y (Sry) 抗体 sex determining region of Chr Y (Sry) 抗体 SRXX1 抗体 SRXY1 抗体 SRY 抗体 Sry1 抗体 Sry3BI 抗体 SRYGENE 抗体 TDF 抗体 Tdf 抗体 TDY 抗体 Tdy 抗体