SPHK2 抗体
(Sphingosine Kinase 2 (SPHK2))
This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011].
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Latest Publications for our SPHK2 抗体
: "Sphingosine kinase 2 activates autophagy and protects neurons against ischemic injury through interaction with Bcl-2 via its putative BH3 domain." in: Cell death & disease, Vol. 8, Issue 7, pp. e2912, (2018) (PubMed).: "Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD." in: PLoS ONE, Vol. 12, Issue 11, pp. e0179577, (2017) (PubMed).
: "Hypoxic preconditioning protects cardiomyocytes against hypoxia/reoxygenation-induced cell apoptosis via sphingosine kinase 2 and FAK/AKT pathway." in: Experimental and molecular pathology, Vol. 100, Issue 1, pp. 51-8, (2016) (PubMed).
: "Hair Cell Loss Induced by Sphingosine and a Sphingosine Kinase Inhibitor in the Rat Cochlea." in: Neurotoxicity research, Vol. 29, Issue 1, pp. 35-46, (2016) (PubMed).
: "Cigarette smoke inhibits efferocytosis via deregulation of sphingosine kinase signaling: reversal with exogenous S1P and the S1P analogue FTY720." in: Journal of leukocyte biology, Vol. 100, Issue 1, pp. 195-202, (2016) (PubMed).
: "Sphingosine-1-phosphate is involved in the occlusive arteriopathy of pulmonary arterial hypertension." in: Pulmonary circulation, Vol. 6, Issue 3, pp. 369-80, (2016) (PubMed).
: "Down-regulation of Sphk2 suppresses bladder cancer progression." in: Tumour biology, (2015) (PubMed).
: "Preconditioning stimuli induce autophagy via sphingosine kinase 2 in mouse cortical neurons." in: The Journal of biological chemistry, Vol. 289, Issue 30, pp. 20845-57, (2014) (PubMed).
: "Membrane vesicles containing matrix metalloproteinase-9 and fibroblast growth factor-2 are released into the extracellular space from mouse mesoangioblast stem cells." in: Journal of cellular physiology, Vol. 224, Issue 1, pp. 144-51, (2010) (PubMed).
: "Cleavage of sphingosine kinase 2 by caspase-1 provokes its release from apoptotic cells." in: Blood, Vol. 115, Issue 17, pp. 3531-40, (2010) (PubMed).
Aliases for SPHK2 抗体
Sphingosine kinase (sphK2) 抗体sphk2 (sphK2) 抗体
Sphingosine kinase 2 (Sk2) 抗体
sphingosine kinase 2 (SPHK2) 抗体
sphingosine kinase 2 (Sphk2) 抗体
C76851 抗体
CG2159 抗体
CG32484 抗体
DKFZp469F224 抗体
Dmel\\CG32484 抗体
SK-2 抗体
SK2 抗体
sk2 抗体
SK 2 抗体
Sphk2 抗体
SPK-2 抗体
SPK 2 抗体
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