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SPHK2 抗体 (Long Isoform, N-Term)

SPHK2 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4620350
发货至: 中国
  • 抗原 See all SPHK2 抗体
    SPHK2 (Sphingosine Kinase 2 (SPHK2))
    抗原表位
    • 15
    • 12
    • 9
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Long Isoform, N-Term
    适用
    • 63
    • 27
    • 25
    宿主
    • 61
    • 2
    克隆类型
    • 63
    多克隆
    标记
    • 33
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPHK2 antibody is un-conjugated
    应用范围
    • 43
    • 35
    • 32
    • 13
    • 13
    • 9
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detetcts Sphingosine Kinase 2 (Long Form).
    纯化方法
    Ligand affinity chromatography
    免疫原
    Synthetic peptide derived from the N-terminal extension of the Sphingosine Kinase 2-L protein
    亚型
    IgG
    Top Product
    Discover our top product SPHK2 Primary Antibody
  • 应用备注
    Western blot: (1-5 μg/mL). Positive control: Jurkat lysate. ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Upon arrival, aliquot and freeze at -20 °C to -70 °C.
  • 抗原
    SPHK2 (Sphingosine Kinase 2 (SPHK2))
    别名
    Sphingosine Kinase 2 / SPK2 (SPHK2 产品)
    别名
    CG2159 antibody, CG32484 antibody, Dmel\\CG32484 antibody, SK2 antibody, Sphk2 antibody, sk2 antibody, DKFZp469F224 antibody, SK 2 antibody, SK-2 antibody, SPK 2 antibody, SPK-2 antibody, C76851 antibody, Sphingosine kinase antibody, sphk2 antibody, Sphingosine kinase 2 antibody, sphingosine kinase 2 antibody, sphK2 antibody, Sk2 antibody, SPHK2 antibody, Sphk2 antibody
    背景
    The long form of sphingosine kinase 2 (Sphk2-L) is a species-specific isoform of the Sphk2 enzyme expressed in human but not in mouse. It is an N-terminal extended form of Sphk2, extended by 36 amino acids. It functions as expected, catalyzing the formation of sphingosine 1-phosphate from sphingosine, however it appears to have a decreased ability to inhibit DNA synthesis as compared to Sphk2-S (short form of Sphk2). Under normal cellular conditions, Sphk2-L does not appear to inhibit DNA synthesis, but under serum deprivation, SphK2-L translocates to the nucleus and accumlates. This accumlation may be involved in the cessation of cell proliferation or apoptosis depending on the cell type.Synonyms: SK2, SPHK2
    基因ID
    56848
    NCBI登录号
    NP_064511
    UniProt
    Q9NRA0
    途径
    VEGF Signaling
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