SMPD3 抗体
(Sphingomyelin Phosphodiesterase 3 (SMPD3))
Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Acts as a regulator of postnatal development and participates in bone and dentin mineralization. Overexpression enhances cell death, suggesting that it may be involved in apoptosis control. May be involved in IL-1-beta-induced JNK activation in hepatocytes. May act as a mediator in transcriptional regulation of NOS2/iNOS via the NF- kappa-B activation under inflammatory conditions.
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28 results :
SMPD3
适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔
WB
宿主: 兔
Polyclonal
unconjugated
1 reference
Latest Publications for our SMPD3 抗体
: "TSAP6 is a novel candidate marker of poor survival in metastatic high-grade serous carcinoma." in: Human pathology, Vol. 60, pp. 180-187, (2016) (PubMed).: "Dysregulated sphingolipid metabolism in endometriosis." in: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 10, pp. E1913-21, (2014) (PubMed).
: "Analysis of membrane topology of neutral sphingomyelinase 2." in: FEBS letters, Vol. 581, Issue 7, pp. 1323-8, (2007) (PubMed).
Aliases for SMPD3 抗体
sphingomyelin phosphodiesterase 3 (SMPD3) 抗体sphingomyelin phosphodiesterase 3, neutral (Smpd3) 抗体
sphingomyelin phosphodiesterase 3 (Smpd3) 抗体
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